IL12RB2 抗体
Quick Overview for IL12RB2 抗体 (ABIN2854423)
抗原
See all IL12RB2 抗体适用
宿主
克隆类型
标记
应用范围
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交叉反应
- 人
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产品特性
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Rabbit polyclonal antibody to IL-12 Receptor beta2 (interleukin 12 receptor, beta 2)
IL-12 Receptor beta2 antibody [N3C2], Internal -
纯化方法
- Purified by antigen-affinity chromatography.
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免疫原
- Recombinant protein encompassing a sequence within the center region of human IL12 Receptor beta2. The exact sequence is proprietary.
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亚型
- IgG
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anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (AA 301-400) antibody
IL12RB2 适用: 人 WB, ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (AA 1-862) antibodyIL12RB2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (AA 105-214) antibodyIL12RB2 适用: 人 WB, ELISA 宿主: 小鼠 Monoclonal 2H6 unconjugated
anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (AA 756-783) antibodyIL12RB2 适用: 人 WB, IHC, FACS, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (AA 759-788), (C-Term) antibodyIL12RB2 适用: 人 WB, FACS, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (AA 559-647) antibodyIL12RB2 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (AA 285-441) antibodyIL12RB2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (AA 366-470) antibodyIL12RB2 适用: 人 ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (AA 1-862) antibodyIL12RB2 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Interleukin 12 Receptor, beta 2 (IL12RB2) (C-Term) antibodyIL12RB2 适用: 人, 小鼠 WB, ELISA 宿主: 兔 Polyclonal unconjugated
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应用备注
- WB: 1:1000-1:10000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
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说明
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Positive Control: A431 , HepG2
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- 0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- 4 °C,-20 °C
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储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- IL12RB2 (Interleukin 12 Receptor, beta 2 (IL12RB2))
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别名
- interleukin 12 receptor subunit beta 2
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背景
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The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohn's disease and leprosy, which is thought to contribute to the inflammatory response and host defense.
Cellular Localization: Membrane, Single-pass type I membrane protein -
分子量
- 97 kDa
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基因ID
- 3595
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UniProt
- Q99665
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途径
- JAK/STAT Signaling
抗原
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