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ODC1 抗体

Cited in 1 publication. The 兔 多克隆 anti-ODC1 antibody (ABIN2854335) specifically detects ODC1 in WB 和 IHC (p). The antibody is reactive with 人 samples.
产品编号 ABIN2854335
发货至: 中国
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Quick Overview for ODC1 抗体 (ABIN2854335)

抗原

See all ODC1 抗体
ODC1 (Ornithine Decarboxylase 1 (ODC1))

适用

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宿主

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克隆类型

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多克隆

标记

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This ODC1 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
  • 交叉反应

    人, 小鼠, 大鼠

    产品特性

    Rabbit polyclonal antibody to ODC (ornithine decarboxylase 1)
    ODC antibody [N3C3]

    纯化方法

    Purified by antigen-affinity chromatography.

    免疫原

    Recombinant protein encompassing a sequence within the center region of human ODC. The exact sequence is proprietary.

    亚型

    IgG
  • 应用备注

    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.

    说明

    Positive Control: HepG2

    Validation: Orthogonal

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1.19 mg/mL

    缓冲液

    1XPBS pH 7, 20 % Glycerol, 0.025 % ProClin 300

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C,-20 °C

    储存方法

    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • Sekiguchi, Seki, Kawai, Yoshida, Yoshida, Isobe, Hoshino, Shirai, Tanaka, Souzaki, Watanabe, Arakawa, Nannya, Suzuki, Fujii, Kataoka, Shiraishi, Chiba, Tanaka, Shimamura, Sato, Sato-Otsubo, Kimura et al.: "Integrated multiomics analysis of hepatoblastoma unravels its heterogeneity and provides novel druggable targets. ..." in: NPJ precision oncology, Vol. 4, pp. 20, (2020) (PubMed).

  • 抗原

    ODC1 (Ornithine Decarboxylase 1 (ODC1))

    别名

    ornithine decarboxylase 1

    背景

    This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter.

    分子量

    51 kDa

    基因ID

    4953

    UniProt

    P11926
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