Prostate Specific Antigen 抗体 (HRP)
Quick Overview for Prostate Specific Antigen 抗体 (HRP) (ABIN2853634)
抗原
See all Prostate Specific Antigen (PSA) 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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特异性
- This antibody is reactive to normal prostate, benign prostate hyperplasia and prostate malignant carcinoma. Does not cross react with normal human tissues tested.
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纯化方法
- Affinity Chromatography on Protein G
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免疫原
- Human Prostate Specific Antigen
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亚型
- IgG1
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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缓冲液
- 0.01 M PBS, pH 7.0 ± 0.1 in 50 % Glycerol
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储存液
- Thimerosal (Merthiolate)
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注意事项
- This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody prior to reconstitution at -20 °C. Following reconstitution the antibody can be stored at 2-8 °C for one month or at -20 °C for longer.
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- Prostate Specific Antigen (PSA)
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别名
- Kallikrein-3 / PSA / KLK3
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背景
- Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates two transcript variants encoding different isoforms. Additional transcript variants have been described, but it is unclear if these transcripts are normally expressed or if they are specific to benign or malignant tumors.Synonyms: Gamma-seminoprotein, P-30 antigen, Prostate-specific antigen, Semenogelase
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基因ID
- 354
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NCBI登录号
- NP_001025218
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UniProt
- P07288
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途径
- Complement System
抗原
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