SLUG 抗体 (Middle Region)
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北京 101111
Quick Overview for SLUG 抗体 (Middle Region) (ABIN2853627)
抗原
See all SLUG (SNAI2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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特异性
- This antibody detects SLUG at center.
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纯化方法
- Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
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免疫原
- This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the central region of human SLUG.
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亚型
- Ig Fraction
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anti-Snail Family Zinc Finger 2 (SNAI2) (AA 97-169) antibody
SNAI2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 3C12 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 100-200) antibodySNAI2 适用: 人 WB, ELISA, IHC, FACS, ICC 宿主: 小鼠 Monoclonal 4B6D5 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 97-169) antibodySNAI2 适用: 人 WB, ELISA, IF 宿主: 小鼠 Monoclonal 2F11 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 98-129) antibodySNAI2 适用: 人, 小鼠 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 89-268) antibodySNAI2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 126-268) antibodySNAI2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) antibodySNAI2 适用: 人 WB, IHC, IF, FACS, IHC (p) 宿主: 小鼠 Monoclonal 1G7 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 69-132) antibodySNAI2 适用: 人 ELISA 宿主: 小鼠 Monoclonal 2E10 unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (AA 116-148), (Middle Region) antibodySNAI2 适用: 人, 小鼠, 大鼠 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Snail Family Zinc Finger 2 (SNAI2) (Middle Region) antibodySNAI2 适用: 人, 小鼠, 大鼠, Cow, 绵羊, 犬, 马, 兔, 豚鼠, Saccharomyces cerevisiae WB, IHC 宿主: 兔 Polyclonal unconjugated
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应用备注
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ELISA 1: 1,000. Western blot 1: 100 - 1: 500. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
限制
- 仅限研究用
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浓度
- 0.25 mg/mL
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缓冲液
- PBS with 0.09 % (W/V) sodium azide
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储存液
- Sodium azide
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注意事项
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freezing and thawing.
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储存条件
- 4 °C/-20 °C
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储存方法
- Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
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: "Androgen receptor inhibits epithelial-mesenchymal transition, migration, and invasion of PC-3 prostate cancer cells." in: Cancer letters, Vol. 369, Issue 1, pp. 103-11, (2015) (PubMed).
: "Inhibiting interactions of lysine demethylase LSD1 with snail/slug blocks cancer cell invasion." in: Cancer research, Vol. 73, Issue 1, pp. 235-45, (2013) (PubMed).
: "Biological roles and prognostic values of the epithelial-mesenchymal transition-mediating transcription factors Twist, ZEB1 and Slug in diffuse large B-cell lymphoma." in: Histopathology, Vol. 62, Issue 2, pp. 326-33, (2012) (PubMed).
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: "Androgen receptor inhibits epithelial-mesenchymal transition, migration, and invasion of PC-3 prostate cancer cells." in: Cancer letters, Vol. 369, Issue 1, pp. 103-11, (2015) (PubMed).
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- SLUG (SNAI2) (Snail Family Zinc Finger 2 (SNAI2))
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别名
- SNAI2 / SLUG
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背景
- SLUG is a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporadic cases of neural tube defects.Synonyms: Neural crest transcription factor Slug, Protein snail homolog 2, SLUGH, Zinc finger protein SNAI2
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分子量
- 29986 Da
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基因ID
- 6591, 9606
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UniProt
- O43623
抗原
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