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CD44 抗体 (FITC)

This anti-CD44 antibody is a 小鼠 单克隆 antibody detecting CD44 in FACS. Suitable for 人.
产品编号 ABIN2853597
发货至: 中国

Quick Overview for CD44 抗体 (FITC) (ABIN2853597)

抗原

See all CD44 抗体
CD44

适用

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宿主

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小鼠

克隆类型

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单克隆

标记

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This CD44 antibody is conjugated to FITC

应用范围

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Flow Cytometry (FACS)

克隆位点

15C6
  • 特异性

    This antibody reacts with CD44 antigen.

    交叉反应 (详细)

    Species reactivity (tested):Human

    纯化方法

    Protein A agarose beads

    免疫原

    MML-1 human leukemia cells

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    0.05 mg/mL

    缓冲液

    PBS, 0.09 % NaN3, 1 % BSA

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C

    储存方法

    Store at 2-8 °C.
  • 抗原

    CD44

    别名

    CD44

    背景

    CD44, also known as H-CAM, Homing Cell Adhesion Molecule, and Pgp-1 is a highly glycosylated transmembrane protein expressed by lymphocytes, fibroblasts, smooth muscle cells, and epithelial cells. CD44 functions as lymphocyte adhesion molecule, acting as a matrix receptor that mediates cell adhesion to the extracellular matrix. CD44 is also involved in T-lymphocyte activation, lymphocyte homing, cell migration, and hematopoiesis. Expression of CD44 on the cell surface changes profoundly during tumor metastasis, and the transition from non-metastatic to metastatic tumor cell variants is associated with expression of CD44 variants (CD44v's), making CD44 a potential cancer marker. CD44 has a predicted molecular weight of 85-90 kDa, but glycosylation can increase the apparent MW to ~200 kDa.Synonyms: CDw44, ECMR-III, Epican, Extracellular matrix receptor III, GP90 lymphocyte homing/adhesion receptor, HUTCH-I, Heparan sulfate proteoglycan, Hermes antigen, Hyaluronate receptor, LHR, MDU2, MDU3, MIC4, PGP-1, Phagocytic glycoprotein 1

    基因ID

    960

    NCBI登录号

    NP_000601

    UniProt

    P16070

    途径

    Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
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