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Cyclin A 抗体 (Biotin)

The Biotin-conjugated 小鼠 单克隆 anti-Cyclin A antibody (Clone E67-1) (ABIN2853583) specifically detects Cyclin A in WB 和 IP. The antibody is reactive with 人, 小鼠 和 大鼠 samples.
产品编号 ABIN2853583
发货至: 中国
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Quick Overview for Cyclin A 抗体 (Biotin) (ABIN2853583)

抗原

See all Cyclin A (CCNA2) 抗体
Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

适用

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人, 小鼠, 大鼠

宿主

  • 90
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  • 1
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小鼠

克隆类型

  • 85
  • 48
单克隆

标记

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This Cyclin A antibody is conjugated to Biotin

应用范围

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Western Blotting (WB), Immunoprecipitation (IP)

克隆位点

E67-1
  • 特异性

    This antibody reacts with Cyclin A (55 kDa).

    纯化方法

    Protein-A Agarose Chromatography of hybridoma supernatant.

    免疫原

    Bovine recombinant Cyclin A.

    亚型

    IgG2a
  • 应用备注

    Optimal working dilution should be determined by the investigator.

    限制

    仅限研究用
  • 浓度

    20 µg/mL

    缓冲液

    PBS, pH 7.2 containing 1 % BSA as stabilizer and 0.09 % Sodium Azide as preservative.

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freezing and thawing.

    储存条件

    -20 °C

    储存方法

    Store the antibody (in aliquots) at -20 °C.
  • 抗原

    Cyclin A (CCNA2) (Cyclin A2 (CCNA2))

    别名

    Cyclin A2

    背景

    Cyclin A is a 60 kDa cyclin that binds both cdk2 and p34cdc2 (cdk1), giving two distinct cyclin A kinase activities, one appearing in G1/S phase, the other in G2/M. The level of cyclin A protein peaks in S-phase, and the activity of the cdk2-cyclin A complexes is essential for DNA replication and progression through S phase. Cyclin A is thus a marker for actively proliferating cells and for cells in S-phase. In normal cells, cdk2-cyclin A complexes associate with PCNA and p21CIPP1/WAF1. In addition, cyclin A has been implicated in cell transformation and is found in complexes with E1A, transcrIPPtion factors DRT F1 and E2F, and retinoblastoma protein, p110.Synonyms: CCN1, CCNA, CCNA2, Cyclin A, Cyclin-A2

    基因ID

    890

    NCBI登录号

    NP_001228

    UniProt

    P20248

    途径

    PI3K-Akt Signaling, Cell Division Cycle, AMPK Signaling, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Synthesis of DNA
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