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BCL3 抗体 (Center)

Cited in 1 publication. This 兔 多克隆 anti-BCL3 antibody (Clone RB23954) specifically detects BCL3 in WB, IF, FACS 和 IHC (p). The antibody is reactive with 人 和 小鼠 samples.
产品编号 ABIN653286
发货至: 中国
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Quick Overview for BCL3 抗体 (Center) (ABIN653286)

抗原

See all BCL3 抗体
BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

适用

  • 36
  • 35
  • 4
人, 小鼠

宿主

  • 44
  • 8
  • 5

克隆类型

  • 46
  • 11
多克隆

标记

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This BCL3 antibody is un-conjugated

应用范围

  • 42
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Western Blotting (WB), Immunofluorescence (IF), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

克隆位点

RB23954
  • 抗原表位

    • 15
    • 6
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    AA 249-277, Center

    特异性

    This BCL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 248~277 amino acids from the Center region of human BCL3.

    纯化方法

    This antibody is purified through a protein A column, followed by peptide affinity purification.

    免疫原

    This BCL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 249-277 AA from the Central region of human BCL3.

    亚型

    Ig Fraction
  • 应用备注

    WB = 1:1000, IHC (p) = 1:10-50, IF = 1:10-50, FACS = 1:10-50

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.48 mg/mL

    缓冲液

    PBS with 0.09 % (W/V) sodium azide

    储存液

    Sodium azide

    注意事项

    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    储存条件

    4 °C/-20 °C

    储存方法

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    有效期

    6 months
  • Gehrke, Wörns, Huber, Hess, Straub, Hövelmeyer, Waisman, Kim, Schuppan, Galle, Schattenberg: "Hepatic B cell leukemia-3 promotes hepatic steatosis and inflammation through insulin-sensitive metabolic transcription factors." in: Journal of hepatology, Vol. 65, Issue 6, pp. 1188-1197, (2018) (PubMed).

  • 抗原

    BCL3 (B-Cell CLL/lymphoma 3 (BCL3))

    别名

    BCL3

    背景

    BCL3 is a proto-oncogene candidate. It is identified by its translocation into the immunoglobulin alpha-locus in some cases of B-cell leukemia. The protein contains seven ankyrin repeats, which are most closely related to those found in I kappa B proteins. This protein functions as a transcriptional co-activator that activates through its association with NF-kappa B homodimers.
    Synonyms: Proto-oncogene BCL3, B-cell lymphoma 3 protein, BCL-3, D19S37, BCL4, BCL3

    分子量

    46800 Da

    基因ID

    602

    UniProt

    P20749

    途径

    NF-kappaB Signaling, Maintenance of Protein Location, Protein targeting to Nucleus
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