F12 抗体 (Light Chain) (AbBy Fluor® 594)
Quick Overview for F12 抗体 (Light Chain) (AbBy Fluor® 594) (ABIN2813028)
抗原
See all F12 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Light Chain
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交叉反应
- 人, 小鼠, 大鼠
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纯化方法
- Purified by Protein A.
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免疫原
- KLH conjugated synthetic peptide derived from human Coagulation factor XIIa light chain
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亚型
- IgG
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anti-Coagulation Factor XII (F12) (AA 400-615) antibody
F12 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XII (F12) (AA 352-587) antibodyF12 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XII (F12) (AA 191-300) antibodyF12 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 3A3 unconjugated
anti-Coagulation Factor XII (F12) antibodyF12 适用: 人 ELISA, IHC, IP, IHC (p), IEP 宿主: 山羊 Polyclonal unconjugated
anti-Coagulation Factor XII (F12) (C-Term) antibodyF12 适用: 人, 大鼠 WB, ELISA, IHC, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XII (F12) (Cleaved-Arg372) antibodyF12 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XII (F12) (AA 486-600) antibodyF12 适用: 人 ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XII (F12) antibodyF12 适用: 人, 小鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Coagulation Factor XII (F12) (N-Term) antibodyF12 适用: 人, 猴 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- IF(IHC-P)(1:50-200)
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 μg/μL
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缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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储存条件
- -20 °C
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储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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有效期
- 12 months
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- F12 (Coagulation Factor XII (F12))
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别名
- Factor XII
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背景
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Synonyms: Factor XII, Coagulation factor XIIa light chain, Factor XII, Coagulation factor XII, Factor XII light chain, F12, F12 deficiency, FA12_HUMAN, Factor XII deficiency, HAE3, HAEX, HAF, HAF deficiency, Hageman factor, Beta-factor XIIa part 2.
Background: This gene encodes coagulation factor XII which circulates in blood as a zymogen. This single chain zymogen is converted to a two-chain serine protease with an heavy chain (alpha-factor XIIa) and a light chain. The heavy chain contains two fibronectin-type domains, two epidermal growth factor (EGF)-like domains, a kringle domain and a proline-rich domain, whereas the light chain contains only a catalytic domain. On activation, further cleavages takes place in the heavy chain, resulting in the production of beta-factor XIIa light chain and the alpha-factor XIIa light chain becomes beta-factor XIIa heavy chain. Prekallikrein is cleaved by factor XII to form kallikrein, which then cleaves factor XII first to alpha-factor XIIa and then to beta-factor XIIa. The active factor XIIa participates in the initiation of blood coagulation, fibrinolysis, and the generation of bradykinin and angiotensin. It activates coagulation factors VII and XI. Defects in this gene do not cause any clinical symptoms and the sole effect is that whole-blood clotting time is prolonged. [provided by RefSeq, Jul 2008].
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基因ID
- 2161
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途径
- Complement System
抗原
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