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YBX1 抗体 (pSer102) (AbBy Fluor® 594)

This anti-YBX1 antibody is a 兔 多克隆 antibody detecting YBX1 in WB, IF (cc) 和 IF (p). Suitable for 人 和 大鼠.
产品编号 ABIN2807595
发货至: 中国

Quick Overview for YBX1 抗体 (pSer102) (AbBy Fluor® 594) (ABIN2807595)

抗原

See all YBX1 抗体
YBX1 (Y Box Binding Protein 1 (YBX1))

适用

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人, 大鼠

宿主

  • 91
  • 32

克隆类型

  • 82
  • 41
多克隆

标记

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  • 2
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  • 2
  • 1
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This YBX1 antibody is conjugated to AbBy Fluor® 594

应用范围

  • 82
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  • 5
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Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
  • 抗原表位

    • 24
    • 8
    • 7
    • 4
    • 3
    • 3
    • 2
    • 2
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    • 1
    • 1
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer102

    特异性

    This antibody will recognize Y Box-binding protein 3 when phosphorylated at Ser134

    交叉反应

    人, 大鼠

    预测反应

    Mouse,Dog,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig

    纯化方法

    Purified by Protein A.

    免疫原

    KLH conjugated synthetic phosphopeptide derived from human YB1 around the phosphorylation site of Ser102

    亚型

    IgG
  • 应用备注

    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 μg/μL

    缓冲液

    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

    储存液

    ProClin

    注意事项

    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

    储存条件

    -20 °C

    储存方法

    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

    有效期

    12 months
  • 抗原

    YBX1 (Y Box Binding Protein 1 (YBX1))

    别名

    YB1

    背景

    Synonyms: Nuclease-sensitive element-binding protein 1, CCAAT-binding transcription factor I subunit A, CBF-A, DNA-binding protein B, DBPB, Enhancer factor I subunit A, EFI-A, Y-box transcription factor, Y-box-binding protein 1, YB-1, YBX1, NSEP1, YB1

    Background: Mediates pre-mRNA alternative splicing regulation. Binds to splice sites in pre-mRNA and regulates splice site selection. Binds and stabilizes cytoplasmic mRNA. Contributes to the regulation of translation by modulating the interaction between the mRNA and eukaryotic initiation factors (By similarity). Regulates the transcription of numerous genes. Its transcriptional activity on the multidrug resistance gene MDR1 is enhanced in presence of the APEX1 acetylated form at 'Lys-6' and 'Lys-7'. Binds to promoters that contain a Y-box (5'-CTGATTGGCCAA-3'), such as MDR1 and HLA class II genes. Promotes separation of DNA strands that contain mismatches or are modified by cisplatin. Has endonucleolytic activity and can introduce nicks or breaks into double-stranded DNA (in vitro). May play a role in DNA repair. Component of the CRD-mediated complex that promotes MYC mRNA stability. Binds preferentially to the 5'-[CU]CUGCG-3' motif in vitro. The secreted form acts as an extracellular mitogen and stimulates cell migration and proliferation.

    基因ID

    4904

    UniProt

    P67809

    途径

    Regulation of Muscle Cell Differentiation
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