CBP 抗体 (AbBy Fluor® 594)
Quick Overview for CBP 抗体 (AbBy Fluor® 594) (ABIN2803505)
抗原
See all CBP (CREBBP) 抗体适用
宿主
克隆类型
标记
应用范围
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    - 
                                            交叉反应
- 人, 小鼠, 大鼠
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                                            纯化方法
- Purified by Protein A.
- 
                                            免疫原
- KLH conjugated synthetic peptide derived from human KAT3A/CBP
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                                            亚型
- IgG
 
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                                            应用备注
- IF(IHC-P)(1:50-200)
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                                            限制
- 仅限研究用
 
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                                            状态
- Liquid
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                                            浓度
- 1 μg/μL
- 
                                            缓冲液
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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                                            储存液
- Sodium azide
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                                            注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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                                            储存条件
- -20 °C
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                                            储存方法
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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                                            有效期
- 12 months
 
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    - CBP (CREBBP) (CREB Binding Protein (CREBBP))
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                                            别名
- KAT3A/ CBP
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                                            背景
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                        Synonyms: CBP, CBP/p300, CBP_HUMAN, CREB binding protein, CREB-binding protein, CREBBP, Cyclic AMP responsive enhancer binding protein, Cyclic AMP-responsive enhancer binding protein, KAT3A, RSTS, RTS, Rubinstein Taybi syndrome, Rubinstein-Taybi syndrome. Background: Cyclic AMP-regulated gene expression frequently involves a DNA element designated the cAMP-regulated enhancer (CRE). Many transcription factors bind to this element, including the protein CREB, which is activated as a result of phosphorylation by protein kinase A. It has been shown that protein kinase A-mediated CREB phosphorylation results in its binding to a nuclear protein designated CBP (for CREB-binding protein). These findings suggest that CBP has many of the properties expected of a CREB co-activator. Another high molecular weight transcriptional adapter protein, designated p300, is characterized by three cysteine- and histidine-rich regions, of which the most carboxy terminal region specifically binds the adenovirus E1A protein. p300 Molecules lacking an intact E1A binding site bypass E1A repression, even in the presence of high concentrations of E1A. Sequence analysis of CBP and p300 has revealed substantial homology, arguing that these proteins are members of a conserved family of co-activators. 
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                                            基因ID
- 1387
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                                            途径
- TCR Signaling, Interferon-gamma Pathway, Stem Cell Maintenance, Chromatin Binding, Regulation of Lipid Metabolism by PPARalpha
 抗原
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