ADAM17 抗体 (C-Term)
Quick Overview for ADAM17 抗体 (C-Term) (ABIN2798820)
抗原
See all ADAM17 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 794-823, C-Term
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原理
- Rabbit Anti-Human ADAM17 (C-term) Antibody
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免疫原
- This ADAM17 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 794-823 amino acids from the C-terminal region of human ADAM17.
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亚型
- Ig Fraction
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应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000Western blot analysis of ADAM17 Antibody (N-term) in Jurkat cell line lysates (35 μg/lane). ADAM17(arrow) was detected using the purified Pab. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- ADAM17 (ADAM Metallopeptidase Domain 17 (ADAM17))
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别名
- ADAM17
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背景
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Target Description: ADAM17 is a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biologic processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. ADAM17 functions as a tumor necrosis factor-alpha converting enzyme, binds mitotic arrest deficient 2 protein, and also plays a prominent role in the activation of the Notch signaling pathway.
Gene Symbol: ADAM17
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分子量
- 93021 Da
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基因ID
- 6868
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UniProt
- P78536
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途径
- Notch Signaling, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus
抗原
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