Complement Factor H 抗体 (Center)
Quick Overview for Complement Factor H 抗体 (Center) (ABIN2797150)
抗原
See all Complement Factor H (CFH) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 751-780, Center
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原理
- Rabbit Anti-Human CFH (Center) Antibody
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免疫原
- This CFH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 751-780 amino acids from the Central region of human CFH.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Immunohistochemistry, Immunofluorescence
Recommended Dilutions
WB: 1:1000, IHC: 1:50-100, IF: 1:10-50CFH Antibody (Center) . -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.287 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- Complement Factor H (CFH)
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别名
- CFH
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背景
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Target Description: This gene is a member of the Regulator of Complement Activation (RCA) gene cluster and encodes a protein with twenty short concensus repeat (SCR) domains. This protein is secreted into the bloodstream and has an essential role in the regulation of complement activation, restricting this innate defense mechanism to microbial infections. Mutations in this gene have been associated with hemolytic-uremic syndrome (HUS) and chronic hypocomplementemic nephropathy. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Gene Symbol: CFH
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分子量
- 139096 Da
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基因ID
- 3075
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UniProt
- P08603
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途径
- Complement System, Cellular Response to Molecule of Bacterial Origin
抗原
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