EGF 抗体 (C-Term)
Quick Overview for EGF 抗体 (C-Term) (ABIN2796844)
抗原
See all EGF 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1163-1191, C-Term
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原理
- Mouse Anti-Human EGFR (C-term) Antibody
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免疫原
- This EGFR antibody is generated from mice immunized with a KLH conjugated synthetic peptide between 1163-1191 amino acids from the C-terminal region of human EGFR.
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亚型
- IgG1
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应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000EGFR Antibody (C-term) . -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.500 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- EGF (Epidermal Growth Factor (EGF))
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别名
- EGF
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背景
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Target Description: The protein encoded by this gene is a transmembrane glycoprotein that is a member of the protein kinase superfamily. This protein is a receptor for members of the epidermal growth factor family. EGFR is a cell surface protein that binds to epidermal growth factor. Binding of the protein to a ligand induces receptor dimerization and tyrosine autophosphorylation and leads to cell proliferation. Mutations in this gene are associated with lung cancer. Multiple alternatively spliced transcript variants that encode different protein isoforms have been found for this gene.
Gene Symbol: EGFR
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分子量
- 134277 Da
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基因ID
- 1956
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UniProt
- P00533
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途径
- NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
抗原
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