SGOL2 抗体 (Center)
Quick Overview for SGOL2 抗体 (Center) (ABIN2795993)
抗原
See all SGOL2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 391-419, Center
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原理
- Rabbit Anti-Human SGOL2 (Center) Antibody
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免疫原
- This SGOL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 391-419 amino acids from the Central region of human SGOL2.
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亚型
- Ig Fraction
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anti-Shugoshin-Like 2 (SGOL2) (AA 391-419) antibody
SGOL2 适用: 人 WB 宿主: 兔 Polyclonal RB42663 unconjugated
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应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000SGOL2 Antibody (Center) . -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- SGOL2 (Shugoshin-Like 2 (SGOL2))
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别名
- SGOL2
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背景
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Target Description: Cooperates with PPP2CA to protect centromeric cohesin from separase-mediated cleavage in oocytes specifically during meiosis I. Has a crucial role in protecting REC8 at centromeres from cleavage by separase. During meiosis, protects centromeric cohesion complexes until metaphase II/anaphase II transition, preventing premature release of meiosis-specific REC8 cohesin complexes from anaphase I centromeres. Is thus essential for an accurate gametogenesis. May act by targeting PPP2CA to centromeres, thus leading to cohesin dephosphorylation (By similarity). Essential for recruiting KIF2C to the inner centromere and for correcting defective kinetochore attachments.
Gene Symbol: SGOL2
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分子量
- 144739 Da
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基因ID
- 151246
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UniProt
- Q562F6
抗原
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