APC 抗体 (Center) (APC)
Quick Overview for APC 抗体 (Center) (APC) (ABIN2795685)
抗原
See all APC 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- AA 1148-1176, Center
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原理
- Rabbit Anti-Mouse APC (Center) Antibody
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免疫原
- This APC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1148-1176 amino acids from the Central region of human APC.
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亚型
- Ig Fraction
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应用备注
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Western Blot
Recommended Dilutions
WB: 1:1000APC Antibody (Center). -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- APC (Adenomatous Polyposis Coli (APC))
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别名
- APC
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背景
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Target Description: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
Gene Symbol: APC
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分子量
- 311646 Da
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基因ID
- 324
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UniProt
- P25054
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途径
- WNT signaling, Stem Cell Maintenance, Cell-Cell Junction Organization
抗原
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