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APC 抗体 (Center) (APC)

The APC-conjugated 兔 多克隆 anti-APC antibody (ABIN2795685) specifically detects APC in WB. The antibody is reactive with 小鼠 samples.
产品编号 ABIN2795685
发货至: 中国
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Quick Overview for APC 抗体 (Center) (APC) (ABIN2795685)

抗原

See all APC 抗体
APC (Adenomatous Polyposis Coli (APC))

适用

  • 85
  • 52
  • 47
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
小鼠

宿主

  • 107
  • 15
  • 4
  • 2
  • 2

克隆类型

  • 87
  • 43
多克隆

标记

  • 62
  • 8
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This APC antibody is conjugated to APC

应用范围

  • 72
  • 50
  • 40
  • 33
  • 30
  • 26
  • 26
  • 20
  • 18
  • 6
  • 4
  • 3
  • 3
  • 2
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 21
    • 15
    • 12
    • 9
    • 8
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1148-1176, Center

    原理

    Rabbit Anti-Mouse APC (Center) Antibody

    免疫原

    This APC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1148-1176 amino acids from the Central region of human APC.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot
    Recommended Dilutions
    WB: 1:1000APC Antibody (Center).

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    APC (Adenomatous Polyposis Coli (APC))

    别名

    APC

    背景

    Target Description: This gene encodes a tumor suppressor protein that acts as an antagonist of the Wnt signaling pathway. It is also involved in other processes including cell migration and adhesion, transcriptional activation, and apoptosis. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.

    Gene Symbol: APC

    分子量

    311646 Da

    基因ID

    324

    UniProt

    P25054

    途径

    WNT signaling, Stem Cell Maintenance, Cell-Cell Junction Organization
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