PDK4 抗体 (AA 250-277)
Quick Overview for PDK4 抗体 (AA 250-277) (ABIN2795139)
抗原
See all PDK4 抗体适用
宿主
克隆类型
标记
应用范围
克隆位点
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抗原表位
- AA 250-277
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原理
- Rabbit Anti-Human PDK4 (E265) Antibody
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免疫原
- This PDK4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 250-277 amino acids from human PDK4.
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亚型
- Ig Fraction
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应用备注
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Western Blot, Immunohistochemistry
Recommended Dilutions
WB: 1:1000, IHC: 1:10-50Western blot analysis of PDK4 Antibody (E265) in CEM cell line lysates (35 μg/lane). PDK4 (arrow) was detected using the purified Pab.
Formalin-fixed and paraffin-embedded human skeletal muscle tissue reacted with PDK4-E265, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry, clinical relevance has not been evaluated. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- PDK4 (Pyruvate Dehydrogenase Kinase, Isozyme 4 (PDK4))
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别名
- PDK4
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背景
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Target Description: PDK4 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
Gene Symbol: PDK4
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分子量
- 46469 Da
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基因ID
- 5166
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UniProt
- Q16654
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途径
- PI3K-Akt Signaling, Hedgehog Signaling, Carbohydrate Homeostasis, Regulation of Carbohydrate Metabolic Process, Warburg Effect
抗原
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