MTOR 抗体 (pThr2446)
Quick Overview for MTOR 抗体 (pThr2446) (ABIN2794213)
抗原
See all MTOR (mTOR) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- pThr2446
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原理
- Rabbit Anti-Human Phospho-FRAP1(T2446) Antibody
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免疫原
- This FRAP1 Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding T2446 of human FRAP1.
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亚型
- Ig Fraction
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anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) (AA 2436-2492) antibody
mTOR 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) (C-Term) antibodymTOR 适用: 人, 小鼠, 大鼠 WB, IF, IP, IHC (p), ICC, ChIP 宿主: 兔 Polyclonal unconjugated
anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) (AA 2226-2488) antibodymTOR 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) (AA 2400-2500) antibodymTOR 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) antibodymTOR 适用: 人, 小鼠, 大鼠, 鱼 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) (AA 2311-2529) antibodymTOR 适用: 人 IHC, ELISA 宿主: 小鼠 Monoclonal 8H5A5 unconjugated
anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) (AA 2459-2488) antibodymTOR 适用: 人 WB, IF, IHC (p) 宿主: 兔 Polyclonal RB13347 unconjugated
anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) (AA 2459-2488) antibodymTOR 适用: 人 WB, IHC, ELISA, IF 宿主: 兔 Polyclonal unconjugated
anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) (pSer2481) antibodymTOR 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR) (pSer2448) antibodymTOR 适用: 人, 小鼠, 大鼠, Cow, 鱼 WB, ELISA, FACS, IHC (p), IF (p), IF (cc), IHC (fro) 宿主: 兔 Polyclonal unconjugated
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应用备注
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Dot Blot
Recommended Dilutions
DB: 1:500
Dot blot analysis of anti-FRAP1-pT2446 Phospho-specific Pab on nitrocellulose membrane. 50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 μg per ml. -
限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.450 mg/mL
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储存条件
- 4 °C,-20 °C
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储存方法
- 2-8°C (short-term), -20°C (long-term)
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- MTOR (mTOR) (Mechanistic Target of Rapamycin (serine/threonine Kinase) (mTOR))
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别名
- FRAP1
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背景
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Target Description: FRAP1 belongs to a family of phosphatidylinositol kinase-related kinases. These kinases mediate cellular responses to stresses such as DNA damage and nutrient deprivation. This protein acts as the target for the cell-cycle arrest and immunosuppressive effects of the FKBP12-rapamycin complex. FRAP1 is a part of the TORC2 complex which plays a critical role in AKT1 Ser-473 phosphorylation, and may modulate the phosphorylation of PKCA and regulate actin cytoskeleton organization.
Gene Symbol: MTOR
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分子量
- 288892 Da
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基因ID
- 2475
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UniProt
- P42345
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途径
- PI3K-Akt Signaling, RTK signaling, AMPK Signaling, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Actin Filament Polymerization, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Skeletal Muscle Fiber Development, Regulation of Carbohydrate Metabolic Process, Autophagy, CXCR4-mediated Signaling Events, BCR Signaling, Warburg Effect
抗原
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