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EGF 抗体 (AA 956-985)

This anti-EGF antibody is a 兔 多克隆 antibody detecting EGF in WB. Suitable for 人.
产品编号 ABIN2793119
发货至: 中国

Quick Overview for EGF 抗体 (AA 956-985) (ABIN2793119)

抗原

See all EGF 抗体
EGF (Epidermal Growth Factor (EGF))

适用

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宿主

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克隆类型

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多克隆

标记

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This EGF antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    AA 956-985

    原理

    Rabbit Anti-Human EGFR (Y978) Antibody

    免疫原

    This EGFR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 956-985 amino acids from human EGFR.

    亚型

    Ig Fraction
  • 应用备注

    Western Blot
    Recommended Dilutions
    WB: 1:1000Western blot analysis of EGFR (arrow) using rabbit polyclonal EGFR Antibody .

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    0.5 mg/mL

    储存条件

    4 °C,-20 °C

    储存方法

    2-8°C (short-term), -20°C (long-term)
  • 抗原

    EGF (Epidermal Growth Factor (EGF))

    别名

    EGF

    背景

    Target Description: EGFR is a transmembrane glycoprotein that is a member of a family of protein tyrosine kinases crucial in maintaining a normal balance in cell growth and development. A prototype member of the type 1 receptor tyrosine kinases, EGFR is encoded by the cellular oncogene cerbB1. EGFR has an extracellular ligand binding domain, a single transmembrane region, and cytoplasmic domain which is composed of a tyrosine kinase domain and a carboxy terminal domain. The carboxy terminal domain contains at least four tyrosine autophosphorylation sites. Increased production or activation of EGFR has been associated with poor prognosis in a variety of tumors. EGFR overexpression is observed in tumors of the head and neck, brain, bladder, stomach, breast, lung, endometrium, cervix, vulva, ovary, esophagus, stomach and in squamous cell carcinoma.

    Gene Symbol: EGFR

    分子量

    134277 Da

    基因ID

    1956

    UniProt

    P00533

    途径

    NF-kappaB Signaling, RTK signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Regulation of Carbohydrate Metabolic Process, Hepatitis C, Protein targeting to Nucleus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation
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