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E2F1 抗体 (N-Term)

This 兔多克隆 antibody specifically detects E2F1 in WB. It exhibits reactivity toward 人, 小鼠, 大鼠, 犬, 豚鼠, 兔和马.

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产品编号 ABIN2792603

发货至: 中国

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Quick Overview for E2F1 抗体 (N-Term) (ABIN2792603)

抗原

See all E2F1 抗体

E2F1 (E2F Transcription Factor 1 (E2F1))

适用

人, 小鼠, 大鼠, 犬, 豚鼠, 兔, 马

宿主

兔

克隆类型

多克隆

标记

This E2F1 antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product E2F1 Primary Antibody

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N-Term

序列

PARGRGRHPG KGVKSPGEKS RYETSLNLTT KRFLELLSHS ADGVVDLNWA

交叉反应

牛, 犬, 小鸡, 人, 小鼠, 大鼠

预测反应

Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against E2F1. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human E2F1
anti-E2F Transcription Factor 1 (E2F1) (AA 69-223) antibody
E2F1 适用: 人, 小鼠 WB, ELISA, IHC, FACS 宿主: 小鼠 Monoclonal 8G9 unconjugated

anti-E2F Transcription Factor 1 (E2F1) antibody
E2F1 适用: 人 WB, ELISA, IHC, IF, FACS 宿主: 兔 Monoclonal 1D12 unconjugated Recombinant Antibody

anti-E2F Transcription Factor 1 (E2F1) (AA 348-437) antibody
E2F1 适用: 人 WB, ELISA, PLA 宿主: 小鼠 Monoclonal 2E10 unconjugated

anti-E2F Transcription Factor 1 (E2F1) (AA 101-180) antibody
E2F1 适用: 人, 小鼠, 大鼠 WB, ELISA, FACS, IF (p), IF (cc), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-E2F Transcription Factor 1 (E2F1) (AA 133-362) antibody
E2F1 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated

anti-E2F Transcription Factor 1 (E2F1) antibody
E2F1 适用: 人 WB, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated

anti-E2F Transcription Factor 1 (E2F1) (AA 342-371) antibody
E2F1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated

anti-E2F Transcription Factor 1 (E2F1) (pSer364) antibody
E2F1 适用: 人 WB, ELISA, FACS, IF (p), IF (cc), IHC (p), ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-E2F Transcription Factor 1 (E2F1) (pThr433) antibody
E2F1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-E2F Transcription Factor 1 (E2F1) (C-Term) antibody
E2F1 适用: 人, 小鼠 WB, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

WB Suggested Anti-E2F1 Antibody Titration: 0.2-1 µg/mL
ELISA Titer: 1:1562500
Positive Control: Transfected 293T.
Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 437 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

E2F1 (E2F Transcription Factor 1 (E2F1))

别名

E2F1

背景

The protein encoded by E2F1 is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. The protein encoded by this gene is a member of the E2F family of transcription factors. The E2F family plays a crucial role in the control of cell cycle and action of tumor suppressor proteins and is also a target of the transforming proteins of small DNA tumor viruses. The E2F proteins contain several evolutionally conserved domains found in most members of the family. These domains include a DNA binding domain, a dimerization domain which determines interaction with the differentiation regulated transcription factor proteins (DP), a transactivation domain enriched in acidic amino acids, and a tumor suppressor protein association domain which is embedded within the transactivation domain. This protein and another 2 members, E2F2 and E2F3, have an additional cyclin binding domain. This protein binds preferentially to retinoblastoma protein pRB in a cell-cycle dependent manner. It can mediate both cell proliferation and p53-dependent/independent apoptosis. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: E2F-1, RBBP3, RBP3, RBAP1
Protein Interaction Partner: RB1, SIRT1, KDM2A, LAMTOR5, EP300, KAT2B, VHL, RARA, STAT1, NCOR2, STOML1, RBL1, MAGEA11, SKP2, UHRF2, UBC, GTF2H1, ERCC3, SPT15, TFB1, TBP, NCOA3, CEBPE, PARP1, PRMT2, RBL2, CCNE1, TFDP2, TFDP1, CDKN2A, CEBPD, CDK2, CDK1, NEDD8, MCPH1, DDB2, DDB1, XIAP,
Protein Size: 437

分子量

47 kDa

基因ID

1869

NCBI登录号

NM_005225, NP_005216

UniProt

Q01094

途径

p53 Pathway, Cell Division Cycle, Mitotic G1-G1/S Phases, DNA Replication, M Phase, Autophagy