VEGFR2/CD309 抗体 (N-Term)
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Quick Overview for VEGFR2/CD309 抗体 (N-Term) (ABIN2792307)
抗原
See all VEGFR2/CD309 (VEGFR2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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原理
- KDR Antibody - N-terminal region
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序列
- LNVGIDFNWE YPSSKHQHKK LVNRDLKTQS GSEMKKFLST LTIDGVTRSD
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预测反应
- Cow: 86%, Dog: 100%, Horse: 100%, Human: 100%, Pig: 100%
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产品特性
- This is a rabbit polyclonal antibody against KDR. It was validated on Western Blot using a cell lysate as a positive control.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N terminal region of human KDR
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应用备注
- Optimal working dilution should be determined by the investigator.
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- VEGFR2/CD309 (VEGFR2) (VEGF Receptor 2 (VEGFR2))
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别名
- KDR
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背景
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Background Information: KDR is the receptor for VEGF or VEGFC. It has a tyrosine-protein kinase activity. The VEGF-kinase ligand/receptor signaling system plays a key role in vascular development and regulation of vascular permeability. In case of HIV-1 infection, the interaction with extracellular viral Tat protein seems to enhance angiogenesis in Kaposi's sarcoma lesions.
Gene Name: Kinase insert domain receptor (a type III receptor tyrosine kinase)
Alternative Symbols: FLK1, CD309, VEGFR, VEGFR2
Protein Name: Vascular endothelial growth factor receptor 2
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分子量
- 151kDa
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基因ID
- 3791
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NCBI登录号
- NP_002244
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UniProt
- P35968
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途径
- RTK signaling, Glycosaminoglycan Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2, Growth Factor Binding, Regulation of long-term Neuronal Synaptic Plasticity, VEGF Signaling
抗原
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