电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

Serotonin Receptor 1A 抗体 (N-Term)

Cited in 5+ publications. This anti-Serotonin Receptor 1A antibody is a 兔 多克隆 antibody detecting Serotonin Receptor 1A in WB. Suitable for 人.
产品编号 ABIN2792271
发货至: 中国
Contact our Customer Service for availability and price in your country. Contact Info

Our Local Distributor

中国
北京 101111
No. 88 KeChuang 6th Street
Beijing Economic Technological Development Area
Room 801-803
4A Biotech Co.,Ltd.
Tel +86 (0512) 65829739 传真 +86 (010) 6788 5057

Quick Overview for Serotonin Receptor 1A 抗体 (N-Term) (ABIN2792271)

抗原

See all Serotonin Receptor 1A (HTR1A) 抗体
Serotonin Receptor 1A (HTR1A)

适用

  • 48
  • 32
  • 31
  • 1
  • 1

宿主

  • 42
  • 5
  • 2

克隆类型

  • 45
  • 4
多克隆

标记

  • 23
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This Serotonin Receptor 1A antibody is un-conjugated

应用范围

  • 34
  • 18
  • 13
  • 13
  • 12
  • 8
  • 5
  • 4
  • 3
  • 2
  • 1
Western Blotting (WB)
  • 抗原表位

    • 15
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term

    序列

    GQGNNTTSPP APFETGGNTT GISDVTVSYQ VITSLLLGTL IFCAVLGNAC

    预测反应

    Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against HTR1A. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the N terminal region of human HTR1A
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 422 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Adeosun, Albert, Austin, Iyo: "17?-estradiol-induced regulation of the novel 5-HT1A-related transcription factors NUDR and Freud-1 in SH SY5Y cells." in: Cellular and molecular neurobiology, Vol. 32, Issue 4, pp. 517-21, (2012) (PubMed).

    Szewczyk, Albert, Rogaeva, Fitzgibbon, May, Rajkowska, Miguel-Hidalgo, Stockmeier, Woolverton, Kyle, Wang, Austin: "Decreased expression of Freud-1/CC2D1A, a transcriptional repressor of the 5-HT1A receptor, in the prefrontal cortex of subjects with major depression." in: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 13, Issue 8, pp. 1089-101, (2010) (PubMed).

    Szewczyk, Albert, Burns, Czesak, Overholser, Jurjus, Meltzer, Konick, Dieter, Herbst, May, Rajkowska, Stockmeier, Austin: "Gender-specific decrease in NUDR and 5-HT1A receptor proteins in the prefrontal cortex of subjects with major depressive disorder." in: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 12, Issue 2, pp. 155-68, (2009) (PubMed).

    Cordeaux, Pasupathy, Bacon, Charnock-Jones, Smith: "Characterization of serotonin receptors in pregnant human myometrium." in: The Journal of pharmacology and experimental therapeutics, Vol. 328, Issue 3, pp. 682-91, (2009) (PubMed).

    Iyo, Kieran, Chandran, Albert, Wicks, Bissette, Austin: "Differential regulation of the serotonin 1 A transcriptional modulators five prime repressor element under dual repression-1 and nuclear-deformed epidermal autoregulatory factor by chronic stress." in: Neuroscience, Vol. 163, Issue 4, pp. 1119-27, (2009) (PubMed).

  • 抗原

    Serotonin Receptor 1A (HTR1A)

    别名

    HTR1A

    背景

    This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibits adenylate cyclase activity.
    Alias Symbols: 5HT1a, 5-HT1A, ADRBRL1, ADRB2RL1
    Protein Interaction Partner: UBC, RHOA, GABBR2, GPR26, S1PR1, S1PR3, HTR1D, HTR1B, GNAI3, HTR1A,
    Protein Size: 422

    分子量

    46 kDa

    基因ID

    3350

    NCBI登录号

    NM_000524, NP_000515

    UniProt

    P08908

    途径

    JAK/STAT Signaling, Synaptic Membrane, Feeding Behaviour
You are here: