我们推荐在您的浏览器上开启Javascript，以获得最佳效果。

Serotonin Receptor 1A 抗体 (N-Term)

Name: Serotonin Receptor 1A 抗体 (N-Term)
SKU: ABIN2792271
Availability: OutOfStock

This anti-Serotonin Receptor 1A antibody is a 兔多克隆 antibody detecting Serotonin Receptor 1A in WB. Suitable for 人. This Primary Antibody has been cited in 5+ publications.

Host: Rabbit Target Name: HTR1A Sample Type: Jurkat Lane A: Primary Antibody Lane B: Primary Antibody + Blocking Peptide Primary Antibody Concentration: 1. (Serotonin Receptor 1A 抗体 (N-Term))

Primary cultured neurons 5HT1A Receptors Dilution: Primary: 1:200 Secondary: 1:2000 (Serotonin Receptor 1A 抗体 (N-Term))

HTR1A antibody - N-terminal region (AV) validated by WB using primary cultured neurons (Serotonin Receptor 1A 抗体 (N-Term))

Host: Rabbit Target Name: HTR1A Sample Type: Jurkat Whole Cell lysates Antibody Dilution: 1. (Serotonin Receptor 1A 抗体 (N-Term))

4 images

(5 references)

产品编号 ABIN2792271

发货至: 中国

Datasheet as PDF

Quick Overview for Serotonin Receptor 1A 抗体 (N-Term) (ABIN2792271)

抗原

See all Serotonin Receptor 1A (HTR1A) 抗体

Serotonin Receptor 1A (HTR1A)

适用

人

宿主

兔

克隆类型

多克隆

标记

This Serotonin Receptor 1A antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product HTR1A Primary Antibody

抗原表位
15

5

3

2

2

2

1

1

1

1

1

1

1
N-Term

序列

GQGNNTTSPP APFETGGNTT GISDVTVSYQ VITSLLLGTL IFCAVLGNAC

预测反应

Human: 100%

产品特性

This is a rabbit polyclonal antibody against HTR1A. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the N terminal region of human HTR1A
anti-Serotonin Receptor 1A (HTR1A) antibody
HTR1A 适用: 人 WB, IF, ICC, IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Serotonin Receptor 1A (HTR1A) (AA 301-400) antibody
HTR1A 适用: 人, 大鼠, 小鼠 WB, ELISA, IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated

anti-Serotonin Receptor 1A (HTR1A) antibody
Microarray verified HTR1A 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB765230 unconjugated

anti-Serotonin Receptor 1A (HTR1A) antibody
Microarray verified HTR1A 适用: 人, 小鼠 IHC 宿主: 小鼠 Monoclonal MAB759700 unconjugated

anti-Serotonin Receptor 1A (HTR1A) (AA 230-334) antibody
HTR1A 适用: 人 ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Serotonin Receptor 1A (HTR1A) (AA 239-273) antibody
HTR1A 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB46792 unconjugated

anti-Serotonin Receptor 1A (HTR1A) (N-Term) antibody
HTR1A 适用: 人 WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated

anti-Serotonin Receptor 1A (HTR1A) antibody
Microarray verified HTR1A 适用: 人 IHC 宿主: 小鼠 Monoclonal MAB289500 unconjugated

anti-Serotonin Receptor 1A (HTR1A) (Internal Region) antibody
HTR1A 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated

anti-Serotonin Receptor 1A (HTR1A) antibody
HTR1A 适用: 人, 大鼠 WB, IHC, IHC (p) 宿主: 小鼠 Monoclonal 19A9-2 unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 422 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Adeosun, Albert, Austin, Iyo: "17?-estradiol-induced regulation of the novel 5-HT1A-related transcription factors NUDR and Freud-1 in SH SY5Y cells." in: Cellular and molecular neurobiology, Vol. 32, Issue 4, pp. 517-21, (2012) (PubMed).

Szewczyk, Albert, Rogaeva, Fitzgibbon, May, Rajkowska, Miguel-Hidalgo, Stockmeier, Woolverton, Kyle, Wang, Austin: "Decreased expression of Freud-1/CC2D1A, a transcriptional repressor of the 5-HT1A receptor, in the prefrontal cortex of subjects with major depression." in: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 13, Issue 8, pp. 1089-101, (2010) (PubMed).

Szewczyk, Albert, Burns, Czesak, Overholser, Jurjus, Meltzer, Konick, Dieter, Herbst, May, Rajkowska, Stockmeier, Austin: "Gender-specific decrease in NUDR and 5-HT1A receptor proteins in the prefrontal cortex of subjects with major depressive disorder." in: The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP), Vol. 12, Issue 2, pp. 155-68, (2009) (PubMed).

Cordeaux, Pasupathy, Bacon, Charnock-Jones, Smith: "Characterization of serotonin receptors in pregnant human myometrium." in: The Journal of pharmacology and experimental therapeutics, Vol. 328, Issue 3, pp. 682-91, (2009) (PubMed).

Iyo, Kieran, Chandran, Albert, Wicks, Bissette, Austin: "Differential regulation of the serotonin 1 A transcriptional modulators five prime repressor element under dual repression-1 and nuclear-deformed epidermal autoregulatory factor by chronic stress." in: Neuroscience, Vol. 163, Issue 4, pp. 1119-27, (2009) (PubMed).
抗原

Serotonin Receptor 1A (HTR1A)

别名

HTR1A

背景

This is one of the several different receptors for 5- hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibits adenylate cyclase activity.
Alias Symbols: 5HT1a, 5-HT1A, ADRBRL1, ADRB2RL1
Protein Interaction Partner: UBC, RHOA, GABBR2, GPR26, S1PR1, S1PR3, HTR1D, HTR1B, GNAI3, HTR1A,
Protein Size: 422

分子量

46 kDa

基因ID

3350

NCBI登录号

NM_000524, NP_000515

UniProt

P08908

途径

JAK/STAT Signaling, Synaptic Membrane, Feeding Behaviour