HSPD1 抗体 (C-Term)
Quick Overview for HSPD1 抗体 (C-Term) (ABIN2792215)
抗原
See all HSPD1 抗体适用
宿主
克隆类型
标记
应用范围
-
-
抗原表位
- C-Term
-
序列
- PTKVVRTALL DAAGVASLLT TAEVVVTEIP KEEKDPGMGA MGGMGGGMGG
-
预测反应
- Guinea Pig: 90%, Human: 84%, Rabbit: 84%, Rat: 84%
-
产品特性
- This is a rabbit polyclonal antibody against HSPD1. It was validated on Western Blot using a cell lysate as a positive control.
-
纯化方法
- Affinity Purified
-
免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human HSPD1
-
-
-
-
应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
-
说明
-
Antigen size: 573 AA
-
限制
- 仅限研究用
-
-
-
状态
- Liquid
-
浓度
- Lot specific
-
缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
-
储存液
- Sodium azide
-
注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
注意事项
- Avoid repeated freeze-thaw cycles.
-
储存条件
- -20 °C
-
储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
-
- HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))
-
别名
- HSPD1
-
背景
-
HSPD1 is a member of the chaperonin family. This mitochondrial protein may function as a signaling molecule in the innate immune system. It is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Two pseudogenes, both located on chromosome 8, have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
Alias Symbols: CPN60, GROEL, HSP60, HSP65, HuCHA60, SPG13, HLD4, HSP-60
Protein Interaction Partner: RGS20, NOTCH2NL, KRTAP10-3, KRTAP10-8, SAMD3, KRT40, LZTS2, CEP70, HUWE1, TMCC2, KRT31, KRTAP5-9, FUS, TUBGCP3, AURKB, VCP, UBC, TUBG1, AURKA, SUMO3, LGALS3BP, CDC20, STAU1, LGR4, NEDD8, MDM2, ERG, ASB4, EED, MAPK14, ATP6V1A, RAB1B, C12orf10, NAGK, C11orf
Protein Size: 573 -
分子量
- 61 kDa
-
基因ID
- 3329
-
NCBI登录号
- NM_002156, NP_002147
-
UniProt
- P10809
-
途径
- Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
抗原
-