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MAPK14 抗体 (C-Term)

This anti-MAPK14 antibody is a 兔 多克隆 antibody detecting MAPK14 in WB 和 IHC. Suitable for 人, 小鼠, 大鼠, 兔, Cow, Pig, 绵羊 和 马.
产品编号 ABIN2792183
发货至: 中国

Quick Overview for MAPK14 抗体 (C-Term) (ABIN2792183)

抗原

See all MAPK14 抗体
MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

适用

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人, 小鼠, 大鼠, 兔, Cow, Pig, 绵羊, 马

宿主

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克隆类型

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多克隆

标记

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This MAPK14 antibody is un-conjugated

应用范围

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Western Blotting (WB), Immunohistochemistry (IHC)
  • 抗原表位

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    C-Term

    序列

    YHDPDDEPVA DPYDQSFESR DLLIDEWKSL TYDEVISFVP PPLDQEEMES

    预测反应

    Cow: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 100%

    产品特性

    This is a rabbit polyclonal antibody against MAPK14. It was validated on Western Blot and immunohistochemistry.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human MAPK14
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 360 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    MAPK14 (Mitogen-Activated Protein Kinase 14 (MAPK14))

    别名

    MAPK14

    背景

    MAPK14 encodes a protein which is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various environmental stresses and proinflammatory cytokines. The activation requires its phosphorylation by MAP kinase kinases (MKKs), or its autophosphorylation triggered by the interaction of MAP3K7IP1/TAB1 protein with this kinase. The substrates of this kinase include transcription regulator ATF2, MEF2C, and MAX, cell cycle regulator CDC25B, and tumor suppressor p53, which suggest the roles of this kinase in stress related transcription and cell cycle regulation, as well as in genotoxic stress response.
    Alias Symbols: RK, p38, CSBP, EXIP, Mxi2, CSBP1, CSBP2, CSPB1, PRKM14, PRKM15, SAPK2A, p38ALPHA
    Protein Interaction Partner: MAPKAPK2, ATF2, PDX1, UBC, MARCKSL1, MAP2K3, MAPK14, ATF6, TCEAL1, USP11, PTPN11, OXCT1, NME1, WDR1, HSPD1, TYMS, ADSS, IQGAP1, MKNK1, MAPKAPK3, CNBP, AKT1, CCDC8, OBSL1, RRP1B, RPS6KA4, SRPK1, MAP2K6, MAPK11, NEB, MAZ, MKNK2, EEF2, DUSP9, ZFP36L1, ADRB2,
    Protein Size: 360

    分子量

    41 kDa

    基因ID

    1432

    NCBI登录号

    NM_001315, NP_001306

    UniProt

    Q16539

    途径

    MAPK Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Regulation of Muscle Cell Differentiation, Regulation of Cell Size, Hepatitis C, Toll-Like Receptors Cascades, Autophagy, Thromboxane A2 Receptor Signaling, BCR Signaling, S100 Proteins
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