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CDC25A 抗体 (Middle Region)

The 兔多克隆 anti-CDC25A antibody is suitable to detect CDC25A in samples from 人, 小鼠, 大鼠, 犬, 马, 兔和豚鼠. It has been validated for WB.

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产品编号 ABIN2792169

发货至: 中国

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Quick Overview for CDC25A 抗体 (Middle Region) (ABIN2792169)

抗原

See all CDC25A 抗体

CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

适用

人, 小鼠, 大鼠, 犬, 马, 兔, 豚鼠

宿主

兔

克隆类型

多克隆

标记

This CDC25A antibody is un-conjugated

应用范围

Western Blotting (WB)

Discover our top product CDC25A Primary Antibody

抗原表位
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Middle Region

序列

MELCEPQSYC PMHHQDHKTE LLRCRSQSKV QEGERQLREQ IALLVKDMSP

预测反应

Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

产品特性

This is a rabbit polyclonal antibody against CDC25A. It was validated on Western Blot using a cell lysate as a positive control.

纯化方法

Affinity Purified

免疫原

The immunogen is a synthetic peptide directed towards the middle region of human CDC25A
anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (AA 235-484) antibody
CDC25A 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pSer124) antibody
CDC25A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB07634 unconjugated

anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pSer75) antibody
CDC25A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pThr507) antibody
CDC25A 适用: 人 WB, ELISA, IHC, IF 宿主: 兔 Polyclonal unconjugated

anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pSer178) antibody
CDC25A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pThr507) antibody
CDC25A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (pSer124) antibody
CDC25A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (AA 1-524) antibody
CDC25A 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated

anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (Ser124) antibody
CDC25A 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal RB59086 unconjugated

anti-Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A) (N-Term) antibody
CDC25A 适用: 人, 小鼠, 大鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated

应用备注

Optimal working dilutions should be determined experimentally by the investigator.

说明

Antigen size: 484 AA

限制

仅限研究用
状态

Liquid

浓度

Lot specific

缓冲液

Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

储存液

Sodium azide

注意事项

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

注意事项

Avoid repeated freeze-thaw cycles.

储存条件

-20 °C

储存方法

For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
抗原

CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

别名

CDC25A

背景

CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene. CDC25A is a member of the CDC25 family of phosphatases. CDC25A is required for progression from G1 to the S phase of the cell cycle. It activates the cyclin-dependent kinase CDC2 by removing two phosphate groups. CDC25A is specifically degraded in response to DNA damage, which prevents cells with chromosomal abnormalities from progressing through cell division. CDC25A is an oncogene, although its exact role in oncogenesis has not been demonstrated. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: CDC25A2
Protein Interaction Partner: ANAPC11, FZR1, FBXW11, BTRC, CUL1, SKP1, VCP, UBC, NPLOC4, YWHAQ, SCYL1, CAMK1D, POLR1D, FGF21, CHEK2, CCNI, MCM3AP, VAMP8, CUL3, XPO1, SOX5, PEX19, NFYA, NFKBIB, MTAP, SMAD3, LMO2, IL3RA, HLA-C, FTH1, EEF1A1, DMD, CHEK1, APP, TRIB3, CSNK1A1, CDK2, FAM193
Protein Size: 484

分子量

54 kDa

基因ID

993

NCBI登录号

NM_201567, NP_963861

UniProt

P30304

途径

Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase