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CDK6 抗体 (C-Term)

This anti-CDK6 antibody is a 兔 多克隆 antibody detecting CDK6 in WB. Suitable for 人, 小鼠, 兔, Cow, 犬, 马 和 Pig.
产品编号 ABIN2792149
发货至: 中国

Quick Overview for CDK6 抗体 (C-Term) (ABIN2792149)

抗原

See all CDK6 抗体
CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

适用

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  • 1
人, 小鼠, 兔, Cow, 犬, 马, Pig

宿主

  • 103
  • 18

克隆类型

  • 89
  • 32
多克隆

标记

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This CDK6 antibody is un-conjugated

应用范围

  • 73
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  • 27
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  • 25
  • 17
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  • 2
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Western Blotting (WB)
  • 抗原表位

    • 21
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    • 8
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    • 2
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    C-Term

    序列

    LLKCLTFNPA KRISAYSALS HPYFQDLERC KENLDSHLPP SQNTSELNTA

    预测反应

    Cow: 84%, Dog: 84%, Horse: 84%, Human: 100%, Mouse: 76%, Pig: 84%, Rabbit: 84%

    产品特性

    This is a rabbit polyclonal antibody against CDK6. It was validated on Western Blot using a cell lysate as a positive control.

    纯化方法

    Protein A purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human CDK6
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 326 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    CDK6 (Cyclin-Dependent Kinase 6 (CDK6))

    别名

    CDK6

    背景

    CDK6 is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb.The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb.
    Alias Symbols: MGC59692, PLSTIRE
    Protein Interaction Partner: PSMA3, DAB1, CDKN2D, CDKN2C, CDKN2B, CCND3, UBC, CCND2, AMY2A, CDKN2A, CDK6, PIGR, DMBT1, WDR33, CDKL3, RB1, CDK4, UCHL1, PML, NUMA1, NFATC3, MYC, MLLT3, MEF2D, MCM2, ISL1, HSP90AA1, HSF1, FOXO3, FOXM1, EZH2, ELK1, DDIT3, ATF6B, CDKN1A, CDC6, CCND1, ZSCAN
    Protein Size: 326

    分子量

    37 kDa

    基因ID

    1021

    NCBI登录号

    NM_001259, NP_001250

    UniProt

    Q00534

    途径

    Cell Division Cycle, Mitotic G1-G1/S Phases
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