FANCD2 抗体 (Middle Region)
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北京 101111
Quick Overview for FANCD2 抗体 (Middle Region) (ABIN2792058)
抗原
See all FANCD2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- TPHTVTAISA KIRKKGKIER KQKTDGSKTS SSDTLSEEKN SECDPTPSHR
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预测反应
- Horse: 79%, Human: 100%, Pig: 79%
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产品特性
- This is a rabbit polyclonal antibody against FANCD2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of human FANCD2
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anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (N-Term) antibody
FANCD2 适用: 人, 小鼠 WB, IHC, IF, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (AA 1-230) antibodyFANCD2 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (pSer222) antibodyFANCD2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (N-Term) antibodyFANCD2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (AA 1-291) antibodyFANCD2 适用: 人 IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) antibodyFANCD2 适用: 人 WB 宿主: 兔 Monoclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (pSer222) antibodyFANCD2 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (AA 893-927) antibodyFANCD2 适用: 人 WB 宿主: 兔 Polyclonal RB49367 unconjugated
anti-Fanconi Anemia, Complementation Group D2 (FANCD2) (Ser371) antibodyFANCD2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FANCD2 (Fanconi Anemia, Complementation Group D2 (FANCD2))
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别名
- FANCD2
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背景
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The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity, they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group D2. This protein is monoubiquinated in response to DNA damage, resulting in its localization to nuclear foci with other proteins (BRCA1 AND BRCA2) involved in homology-directed DNA repair. Alternative splicing results in multiple transcript variants.
Alias Symbols: FA4, FAD, FACD, FAD2, FA-D2, FANCD
Protein Size: 749 -
分子量
- 82 kDa
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基因ID
- 2177
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NCBI登录号
- NM_001018115, NP_001018125
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UniProt
- Q9BXW9
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途径
- DNA Damage Repair
抗原
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