CCDC98 抗体 (C-Term)
Quick Overview for CCDC98 抗体 (C-Term) (ABIN2790106)
抗原
See all CCDC98 (FAM175A) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- DDRWQFKRSR LLDTQDKRSK ADTGSSNQDK ASKMSSPETD EEIEKMKGFG
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预测反应
- Cow: 85%, Dog: 79%, Horse: 100%, Human: 100%, Pig: 79%, Rabbit: 100%
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产品特性
- This is a rabbit polyclonal antibody against FAM175A. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-Family with Sequence Similarity 175, Member A (FAM175A) (AA 51-150) antibody
FAM175A 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 175, Member A (FAM175A) (AA 1-313) antibodyFAM175A 适用: 人 WB, IP, ICFC 宿主: 小鼠 Monoclonal ABRA1-01 unconjugated
anti-Family with Sequence Similarity 175, Member A (FAM175A) (AA 350-400) antibodyFAM175A 适用: 人 WB, IP, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Family with Sequence Similarity 175, Member A (FAM175A) (N-Term) antibodyFAM175A 适用: 人, 小鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 409 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CCDC98 (FAM175A) (Family with Sequence Similarity 175, Member A (FAM175A))
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别名
- FAM175A
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背景
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FAM175A is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as a central scaffold protein that assembles the various components of the BRCA1-A complex and mediates the recruitment of BRCA1.
Alias Symbols: ABRA1, CCDC98, FLJ11520, FLJ12642, FLJ13614
Protein Interaction Partner: FANCG, UIMC1, BRCA1, BRCC3, BABAM1, UBC, SUMO2, PAXIP1, MDC1, BARD1, BRE, HSPA4,
Protein Size: 409 -
分子量
- 47 kDa
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基因ID
- 84142
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NCBI登录号
- NM_139076, NP_620775
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UniProt
- Q6UWZ7
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途径
- DNA Damage Repair, Positive Regulation of Response to DNA Damage Stimulus
抗原
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