GPR68 抗体 (Middle Region)
Quick Overview for GPR68 抗体 (Middle Region) (ABIN2789838)
抗原
See all GPR68 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- SIYFLMHEEV IEDENQHRVC FEHYPIQAWQ RAINYYRFLV GFLFPICLLL
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预测反应
- Dog: 79%, Horse: 93%, Human: 100%, Mouse: 93%, Pig: 79%, Rabbit: 79%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against GPR68. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Human GPR68
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 365 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GPR68 (G Protein-Coupled Receptor 68 (GPR68))
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别名
- GPR68
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背景
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Proton-sensing receptor is involved in pH homeostasis. GPR68 may represents an osteoblastic pH sensor regulating cell-mediated responses to acidosis in bone. GPR68 mediates its action by association with G proteins that stimulates inositol phosphate (IP) production or Ca2+ mobilization. The receptor is almost silent at pH 7.8 but fully activated at pH 6.8. Function also as a metastasis suppressor gene in prostate cancer.
Alias Symbols: MGC111379, MGC156983, OGR1, GPR12A
Protein Size: 365 -
分子量
- 41 kDa
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基因ID
- 8111
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NCBI登录号
- NM_003485, NP_003476
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UniProt
- Q15743
抗原
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