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MCAM 抗体 (Middle Region)

MCAM 适用: 人, 兔, Pig, Cow, 马 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2789518
发货至: 中国
  • 抗原 See all MCAM 抗体
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    抗原表位
    • 16
    • 13
    • 11
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    适用
    • 127
    • 48
    • 47
    • 15
    • 13
    • 9
    • 8
    • 7
    • 5
    • 2
    人, 兔, Pig, Cow, 马
    宿主
    • 95
    • 56
    • 1
    • 1
    • 1
    • 1
    克隆类型
    • 86
    • 69
    多克隆
    标记
    • 75
    • 14
    • 13
    • 10
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MCAM antibody is un-conjugated
    应用范围
    • 91
    • 72
    • 66
    • 44
    • 20
    • 20
    • 18
    • 12
    • 12
    • 5
    • 4
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB)
    序列
    PSTREAEEET TNDNGVLVLE PARKEHSGRY ECQGLDLDTM ISLLSEPQEL
    预测反应
    Cow: 86%, Horse: 86%, Human: 100%, Pig: 86%, Rabbit: 79%
    产品特性
    This is a rabbit polyclonal antibody against MCAM. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product MCAM Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 646 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    MCAM (Melanoma Cell Adhesion Molecule (MCAM))
    别名
    MCAM (MCAM 产品)
    别名
    CD146 antibody, MUC18 antibody, Muc18 antibody, 1-gicerin antibody, AV025631 antibody, CD149 antibody, s-endo antibody, s-gicerin antibody, cd146 antibody, gicerin antibody, id:ibd3512 antibody, mcam antibody, MCAM antibody, melanoma cell adhesion molecule antibody, melanoma cell adhesion molecule b antibody, MCAM antibody, Mcam antibody, mcamb antibody
    背景
    MCAM plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. MCAM could be an adhesion molecule active in neural crest cells during embryonic development. MCAM acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.
    Alias Symbols: CD146, MUC18
    Protein Interaction Partner: ADRB2, UBC, HSP90AA5P, HSPA1L, ATF7IP, PTK2B, FYN,
    Protein Size: 646
    分子量
    71 kDa
    基因ID
    4162
    NCBI登录号
    NM_006500, NP_006491
    UniProt
    P43121
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