MCAM 抗体 (C-Term)
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北京 101111
Quick Overview for MCAM 抗体 (C-Term) (ABIN2789517)
抗原
See all MCAM 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- MCAM Antibody - C-terminal region
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序列
- STSTASPHTR ANSTSTERKL PEPESRGVVI VAVIVCILVL AVLGAVLYFL
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预测反应
- Dog: 79%, Guinea Pig: 77%, Horse: 79%, Human: 100%, Mouse: 93%, Pig: 86%, Rabbit: 79%, Rat: 93%
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产品特性
- This is a rabbit polyclonal antibody against MCAM. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human MCAM
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anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 84-189) antibody
MCAM 适用: 人 FACS, IHC, WB, ELISA 宿主: 小鼠 Monoclonal 6C3E6 unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 447-646) antibodyMCAM 适用: 人 IHC, WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 50-646) antibodyMCAM 适用: 人 FACS, WB, IF, ELISA 宿主: 小鼠 Monoclonal 4D10C7 unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 27-621) antibodyMCAM 适用: 小鼠, 大鼠 FACS, IHC, WB, IF, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 59-401) antibodyMCAM 适用: 人 FACS, IHC, WB, IHC (fro) 宿主: 小鼠 Monoclonal 4C12 unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) antibodyMCAM 适用: 人, 小鼠, 大鼠 IHC 宿主: 兔 Polyclonal unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 226-374) antibodyMCAM 适用: 人 IHC 宿主: 小鼠 Monoclonal MCAM-3046 unconjugated
anti-Melanoma Cell Adhesion Molecule (MCAM) antibodyMCAM 适用: 人 FACS, IHC, WB, IF, ELISA 宿主: 兔 Monoclonal 8A10 unconjugated Recombinant Antibody
anti-Melanoma Cell Adhesion Molecule (MCAM) antibodyKD Validated MCAM 适用: 人 FACS, WB 宿主: 兔 Monoclonal 23GB2705 unconjugated Recombinant Antibody
anti-Melanoma Cell Adhesion Molecule (MCAM) (AA 1-646) antibodyMCAM 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP63482-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- MCAM (Melanoma Cell Adhesion Molecule (MCAM))
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别名
- MCAM
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背景
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Background Information: MCAM plays a role in cell adhesion, and in cohesion of the endothelial monolayer at intercellular junctions in vascular tissue. Its expression may allow melanoma cells to interact with cellular elements of the vascular system, thereby enhancing hematogeneous tumor spread. MCAM could be an adhesion molecule active in neural crest cells during embryonic development. MCAM acts as surface receptor that triggers tyrosine phosphorylation of FYN and PTK2, and a transient increase in the intracellular calcium concentration.
Gene Name: melanoma cell adhesion molecule
Alternative Symbols: CD146, MUC18, HEMCAM, METCAM, MelCAM
Protein Name: Cell surface glycoprotein MUC18
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分子量
- 57kDa
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基因ID
- 4162
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UniProt
- P43121
抗原
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