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ABI1 抗体 (C-Term)

This anti-ABI1 antibody is a 兔 多克隆 antibody detecting ABI1 in WB. Suitable for 人, 大鼠, 小鼠, 马, 兔, Cow, 豚鼠, 犬 和 斑马鱼.
产品编号 ABIN2789495
发货至: 中国

Quick Overview for ABI1 抗体 (C-Term) (ABIN2789495)

抗原

See all ABI1 抗体
ABI1 (Abl-Interactor 1 (ABI1))

适用

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人, 大鼠, 小鼠, 马, 兔, Cow, 豚鼠, 犬, 斑马鱼

宿主

  • 70
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克隆类型

  • 70
  • 4
多克隆

标记

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This ABI1 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    IEKVVAIYDY TKDKDDELSF MEGAIIYVIK KNDDGWYEGV CNRVTGLFPG

    预测反应

    Cow: 93%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

    产品特性

    This is a rabbit polyclonal antibody against ABI1. It was validated on Western Blot.

    纯化方法

    Affinity Purified
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 388 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    ABI1 (Abl-Interactor 1 (ABI1))

    别名

    ABI1

    背景

    This gene encodes a member of the Abelson-interactor family of adaptor proteins. These proteins facilitate signal transduction as components of several multiprotein complexes, and regulate actin polymerization and cytoskeletal remodeling through interactions with Abelson tyrosine kinases. The encoded protein plays a role in macropinocytosis as a component of the WAVE2 complex, and also forms a complex with EPS8 and SOS1 that mediates signal transduction from Ras to Rac. This gene may play a role in the progression of several malignancies including melanoma, colon cancer and breast cancer, and a t(10,11) chromosomal translocation involving this gene and the MLL gene has been associated with acute myeloid leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 14.
    Alias Symbols: ABI-1, E3B1, NAP1BP, SSH3BP, SSH3BP1, ABLBP4
    Protein Interaction Partner: ABL1, UBC, PRPF40A, TCERG1, GAS7, APBB1, SRRM1, PRKAA1, PIK3R1, CDC123, CTTN, NCK2, NCK1, CBL, CACNA1A, RYK, EPS8L1, ENAH, MINK1, EVL, NIN, CYFIP2, HSPA8, WASF2, WASF1, PAK2, NCKAP1, ABI1, VASP, SOS2, EPS8, NCF1, SPTA1, SPTAN1, SOS1, NEB, EPS8L3, EPS8L2,
    Protein Size: 388

    分子量

    42 kDa

    基因ID

    10006

    NCBI登录号

    NM_001178124, NP_001171595

    UniProt

    B6VEX5

    途径

    RTK signaling, Response to Water Deprivation, ER-Nucleus Signaling
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