IL13 Receptor alpha 1 抗体 (N-Term)
Quick Overview for IL13 Receptor alpha 1 抗体 (N-Term) (ABIN2789491)
抗原
See all IL13 Receptor alpha 1 (IL13RA1) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- VSVENLCTVI WTWNPPEGAS SNCSLWYFSH FGDKQDKKIA PETRRSIEVP
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预测反应
- Cow: 92%, Dog: 85%, Guinea Pig: 77%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 85%, Rabbit: 100%, Rat: 86%, Sheep: 92%
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产品特性
- This is a rabbit polyclonal antibody against IL13RA1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of IL13RA1
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 427 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IL13 Receptor alpha 1 (IL13RA1) (Interleukin 13 Receptor, alpha 1 (IL13RA1))
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别名
- IL13RA1
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背景
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The protein encoded by this gene is a subunit of the interleukin 13 receptor. This subunit forms a receptor complex with IL4 receptor alpha, a subunit shared by IL13 and IL4 receptors. This subunit serves as a primary IL13-binding subunit of the IL13 receptor, and may also be a component of IL4 receptors. This protein has been shown to bind tyrosine kinase TYK2, and thus may mediate the signaling processes that lead to the activation of JAK1, STAT3 and STAT6 induced by IL13 and IL4.
Alias Symbols: CD213A1, IL-13Ra, NR4
Protein Interaction Partner: UBC, IL2RG, TMEM39B, ELAVL1, TRAF3IP1, DLG4, TYK2, IL4R, IL13,
Protein Size: 427 -
分子量
- 47 kDa
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基因ID
- 3597
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NCBI登录号
- NM_001560, NP_001551
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UniProt
- P78552
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途径
- JAK/STAT Signaling, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
抗原
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