Angiopoietin 2 抗体 (Middle Region)
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Quick Overview for Angiopoietin 2 抗体 (Middle Region) (ABIN2789397)
抗原
See all Angiopoietin 2 (ANGPT2) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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序列
- NQTTRLELQL LQHSISTNKL EKQILDQTSE INKLQNKNSF LEQKVLDMEG
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Pig: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%
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产品特性
- This is a rabbit polyclonal antibody against Angpt2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the middle region of Mouse Angpt2
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anti-Angiopoietin 2 (ANGPT2) (AA 24-165) antibody
ANGPT2 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (AA 19-147) antibodyANGPT2 适用: 小鼠 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) antibodyANGPT2 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (AA 404-432), (C-Term) antibodyANGPT2 适用: 人, 小鼠 WB, IHC (p), FACS 宿主: 兔 Polyclonal RB17789 unconjugated
anti-Angiopoietin 2 (ANGPT2) (AA 401-496) antibodyANGPT2 适用: 人 WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (AA 19-483) antibodyANGPT2 适用: 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (AA 19-485) antibodyANGPT2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (N-Term) antibodyANGPT2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (N-Term) antibodyANGPT2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, ICC, IF 宿主: 兔 Polyclonal unconjugated
anti-Angiopoietin 2 (ANGPT2) (AA 19-348) antibodyANGPT2 适用: 人 IHC 宿主: 兔 Polyclonal unconjugated
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Angiopoietin 2 (ANGPT2)
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别名
- Angpt2
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背景
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Angpt2 binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. It can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
Alias Symbols: Agpt2, Ang-2, Ang2
Protein Size: 496 -
分子量
- 56 kDa
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基因ID
- 11601
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NCBI登录号
- NM_007426, NP_031452
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UniProt
- O35608
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途径
- RTK signaling
抗原
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