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ALOX5 抗体 (C-Term)

This anti-ALOX5 antibody is a 兔 多克隆 antibody detecting ALOX5 in WB. Suitable for 人, 小鼠, 大鼠, Cow, 兔, 犬, 马 和 豚鼠.
产品编号 ABIN2789351
发货至: 中国

Quick Overview for ALOX5 抗体 (C-Term) (ABIN2789351)

抗原

See all ALOX5 抗体
ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

适用

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人, 小鼠, 大鼠, Cow, 兔, 犬, 马, 豚鼠

宿主

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克隆类型

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多克隆

标记

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This ALOX5 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    FGQLFLGMYP EEHFIEKPVK EAMARFRKNL EAIVSVIAER NKKKQLPYYY

    预测反应

    Cow: 86%, Dog: 79%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%

    产品特性

    This is a rabbit polyclonal antibody against ALOX5. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C-terminal region of Human ALOX5
  • 限制

    仅限研究用
  • 状态

    Liquid

    浓度

    1 mg/mL

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeat freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

    别名

    ALOX5

    背景

    This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
    Protein Interaction Partner: CEP57L1, NUTM1, SYCE1, CEP63, HHIPL2, COTL1, MAD1L1, REL, MEOX1, PIK3R1, DICER1, MAPKAPK2, LTC4S, ALOX5AP, APP, TGFBRAP1, GRB2, ACTB,
    Protein Size: 617

    分子量

    67 kDa

    基因ID

    240

    NCBI登录号

    NP_001243083

    UniProt

    B7ZLS0
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