ALOX5 抗体 (C-Term)
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Quick Overview for ALOX5 抗体 (C-Term) (ABIN2789351)
抗原
See all ALOX5 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- FGQLFLGMYP EEHFIEKPVK EAMARFRKNL EAIVSVIAER NKKKQLPYYY
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预测反应
- Cow: 86%, Dog: 79%, Guinea Pig: 92%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 86%, Rat: 86%
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产品特性
- This is a rabbit polyclonal antibody against ALOX5. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human ALOX5
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))
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别名
- ALOX5
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背景
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This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Protein Interaction Partner: CEP57L1, NUTM1, SYCE1, CEP63, HHIPL2, COTL1, MAD1L1, REL, MEOX1, PIK3R1, DICER1, MAPKAPK2, LTC4S, ALOX5AP, APP, TGFBRAP1, GRB2, ACTB,
Protein Size: 617 -
分子量
- 67 kDa
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基因ID
- 240
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NCBI登录号
- NP_001243083
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UniProt
- B7ZLS0
抗原
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