RASGRP4 抗体 (N-Term)
Quick Overview for RASGRP4 抗体 (N-Term) (ABIN2789029)
抗原
See all RASGRP4 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- FWATVAREGN SAQRRLGDSS DLLSPGGPGP PLPMSSPGLG KKRKVSLLFD
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预测反应
- Human: 100%, Pig: 92%
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产品特性
- This is a rabbit polyclonal antibody against RASGRP4. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-RAS Guanyl Releasing Protein 4 (RASGRP4) (AA 574-673) antibody
RASGRP4 适用: 人 WB, ELISA, IHC (p) 宿主: 小鼠 Monoclonal 1F3 unconjugated
anti-RAS Guanyl Releasing Protein 4 (RASGRP4) (N-Term) antibodyRASGRP4 适用: 人 WB, IHC (p), IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-RAS Guanyl Releasing Protein 4 (RASGRP4) (AA 1-673) antibodyRASGRP4 适用: 人 WB, PLA 宿主: 兔 Polyclonal unconjugated
anti-RAS Guanyl Releasing Protein 4 (RASGRP4) (AA 149-198) antibodyRASGRP4 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 576 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- RASGRP4 (RAS Guanyl Releasing Protein 4 (RASGRP4))
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别名
- RASGRP4
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背景
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The protein encoded by this gene is a member of the Ras guanyl nucleotide-releasing protein (RasGRP) family of Ras guanine nucleotide exchange factors. It contains a Ras exchange motif, a diacylglycerol-binding domain, and two calcium-binding EF hands. This protein was shown to activate H-Ras in a cation-dependent manner in vitro. Expression of this protein in myeloid cell lines was found to be correlated with elevated level of activated RAS protein, and the RAS activation can be greatly enhanced by phorbol ester treatment, which suggested a role of this protein in diacylglycerol regulated cell signaling pathways. Studies of a mast cell leukemia cell line expressing substantial amounts of abnormal transcripts of this gene indicated that this gene may play an important role in the final stages of mast cell development. Multiple transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: -
Protein Interaction Partner: HRAS, RAP1A,
Protein Size: 576 -
分子量
- 63 kDa
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基因ID
- 115727
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NCBI登录号
- NM_001146207, NP_001139679
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UniProt
- C0LTP7
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途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
抗原
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