AKR1C3 抗体 (N-Term)
Quick Overview for AKR1C3 抗体 (N-Term) (ABIN970087)
抗原
See all AKR1C3 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- PALENSLKKA QLDYVDLYLI HSPMSLKPGE ELSPTDENGK VIFDIVDLCT
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预测反应
- Cow: 85%, Guinea Pig: 85%, Human: 100%, Mouse: 77%, Pig: 92%, Rabbit: 86%, Rat: 85%
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产品特性
- This is a rabbit polyclonal antibody against AKR1C3. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) antibody
AKR1C3 适用: 人, 大鼠, 小鼠 WB, ELISA, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (AA 1-323) antibodyAKR1C3 适用: 人 WB, IF, IP 宿主: 兔 Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (C-Term) antibodyKO Validated AKR1C3 适用: 人 WB, IF, IP, IHC (p), ICC 宿主: 兔 Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (AA 1-323) antibodyAKR1C3 适用: 人 WB, ELISA, IHC, IP 宿主: 兔 Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (AA 1-323) antibodyAKR1C3 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) antibodyAKR1C3 适用: 人 ELISA, IF, FACS 宿主: 兔 Monoclonal 4D12 unconjugated Recombinant Antibody
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) antibodyAKR1C3 适用: 人, 小鼠 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (C-Term) antibodyVerified AKR1C3 适用: 人 WB, ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) antibodyAKR1C3 适用: 人 WB, IF 宿主: 兔 Monoclonal unconjugated
anti-Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3) (AA 10-36), (N-Term) antibodyAKR1C3 适用: 人 WB, FACS 宿主: 兔 Polyclonal RB22754 unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 323 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- AKR1C3 (Aldo-Keto Reductase Family 1, Member C3 (3-alpha Hydroxysteroid Dehydrogenase, Type II) (AKR1C3))
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别名
- AKR1C3
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背景
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This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols by utilizing NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme catalyzes the reduction of prostaglandin (PG) D2, PGH2 and phenanthrenequinone (PQ), and the oxidation of 9alpha,11beta-PGF2 to PGD2. It may play an important role in the pathogenesis of allergic diseases such as asthma, and may also have a role in controlling cell growth and/or differentiation. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14.
Alias Symbols: DD3, DDX, HA1753, HAKRB, HAKRe, HSD17B5, KIAA0119, hluPGFS
Protein Interaction Partner: UBC, LRIF1, ZHX1, UBE2W, ACIN1, MAGEA11,
Protein Size: 323 -
分子量
- 36 kDa
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基因ID
- 8644
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NCBI登录号
- NM_003739, NP_003730
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UniProt
- P42330
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途径
- Retinoic Acid Receptor Signaling Pathway, Steroid Hormone Biosynthesis, Regulation of Hormone Metabolic Process, Regulation of Hormone Biosynthetic Process, C21-Steroid Hormone Metabolic Process, Protein targeting to Nucleus
抗原
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