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KPNB1 抗体 (N-Term)

KPNB1 适用: 人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN2788708
发货至: 中国
  • 抗原 See all KPNB1 抗体
    KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
    抗原表位
    • 15
    • 4
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    适用
    • 45
    • 17
    • 16
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    人, 小鼠, 大鼠, 犬, Cow, 豚鼠, 马, 兔
    宿主
    • 42
    • 2
    • 1
    • 1
    克隆类型
    • 43
    • 3
    多克隆
    标记
    • 22
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This KPNB1 antibody is un-conjugated
    应用范围
    • 34
    • 13
    • 13
    • 11
    • 10
    • 5
    • 5
    • 4
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB)
    序列
    EHMKESTLEA IGYICQDIDP EQLQDKSNEI LTAIIQGMRK EEPSNNVKLA
    预测反应
    Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
    产品特性
    This is a rabbit polyclonal antibody against KPNB1. It was validated on Western Blot.
    纯化方法
    Affinity Purified
    Top Product
    Discover our top product KPNB1 Primary Antibody
  • 应用备注
    Optimal working dilutions should be determined experimentally by the investigator.
    说明

    Antigen size: 876 AA

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    Lot specific
    缓冲液
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    注意事项
    Avoid repeated freeze-thaw cycles.
    储存条件
    -20 °C
    储存方法
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原
    KPNB1 (Karyopherin (Importin) beta 1 (KPNB1))
    别名
    KPNB1 (KPNB1 产品)
    别名
    Afu1g15720 antibody, AO090005001133 antibody, imb1 antibody, impnb antibody, ipo1 antibody, ipob antibody, ntf97 antibody, IMB1 antibody, IPO1 antibody, IPOB antibody, Impnb antibody, NTF97 antibody, AA409963 antibody, importin beta-1 subunit antibody, Importin beta-1 subunit antibody, karyopherin (importin) beta 1 L homeolog antibody, importin beta 1 antibody, karyopherin subunit beta 1 antibody, karyopherin (importin) beta 1 antibody, AFUA_1G15720 antibody, AOR_1_1974174 antibody, Bm1_57540 antibody, PMAA_065830 antibody, AFLA_083750 antibody, TSTA_085870 antibody, BDBG_07509 antibody, MCYG_00039 antibody, kpnb1.L antibody, LOC100533387 antibody, KPNB1 antibody, Kpnb1 antibody
    背景
    Nucleocytoplasmic transport, a signal- and energy-dependent process, takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor, a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS-containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the nuclear pore complex. In the presence of nucleoside triphosphates and the small GTP binding protein Ran, the complex moves into the nuclear pore complex and the importin subunits dissociate. Importin alpha enters the nucleoplasm with its passenger protein and importin beta remains at the pore. Interactions between importin beta and the FG repeats of nucleoporins are essential in translocation through the pore complex. The protein encoded by this gene is a member of the importin beta family.
    Alias Symbols: IMB1, IPO1, IPOB, Impnb, MGC2155, MGC2156, MGC2157, NTF97
    Protein Interaction Partner: HUWE1, UBC, FUS, SUMO2, SUMO3, STAU1, MDM2, EED, rev, CUL2, NLK, FBXO6, DYRK1B, CLK3, CDK11A, EGFR, SAMHD1, UBD, PTMA, ADRB2, RASSF5, AICDA, UBL4A, VCAM1, TAF10, NOS2, SMAD2, TAF8, TAF3, ITGA4, FN1, ERBB2, CFTR, YWHAE, SMURF1, ECT2, BARD1, MDC1, TP53BP1,
    Protein Size: 876
    分子量
    96 kDa
    基因ID
    3837
    NCBI登录号
    NM_002265, NP_002256
    UniProt
    Q14974
    途径
    Protein targeting to Nucleus
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