BID 抗体 (C-Term)
Quick Overview for BID 抗体 (C-Term) (ABIN2788659)
抗原
See all BID 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- LRNTSRSEED RNRDLATALE QLLQAYPRDM EKEKTMLVLA LLLAKKVASH
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预测反应
- Dog: 86%, Horse: 86%, Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against BID. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 241 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- BID (BH3 Interacting Domain Death Agonist (BID))
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别名
- BID
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背景
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This gene encodes a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. The encoded protein is a member of the BCL-2 family of cell death regulators. It is a mediator of mitochondrial damage induced by caspase-8 (CASP8), CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. Multiple alternatively spliced transcript variants have been found, but the full-length nature of some variants has not been defined.
Alias Symbols: FP497, MGC15319, MGC42355
Protein Interaction Partner: AHCYL1, REL, MCL1, BCL2, BCL2L1, GZMB, CASP3, BAG3, CAV1, SQSTM1, VCP, UBQLN2, RPA2, RPA1, UBC, TUBB2B, FBN3, RBM48, CRNKL1, ZHX1, C14orf1, SETDB1, PLEKHM1, TLE1, GBP2, GAPDH, CRMP1, ITCH, BID, BCL2L2, CASP8, CASP10, YWHAB, BCL2A1, CSNK1E, CASP2, BAK1, CS
Protein Size: 241 -
分子量
- 27 kDa
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基因ID
- 637
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NCBI登录号
- NM_197966, NP_932070
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UniProt
- B3KT21
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途径
- Apoptosis, Caspase Cascade in Apoptosis, Positive Regulation of Endopeptidase Activity
抗原
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