CD44 抗体 (C-Term)
Quick Overview for CD44 抗体 (C-Term) (ABIN2788656)
抗原
See all CD44 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- SGNGAVEDRK PSGLNGEASK SQEMVHLVNK ESSETPDQFM TADETRNLQN
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预测反应
- Cow: 79%, Dog: 86%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 86%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against CD44. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human CD44
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 361 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- CD44
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别名
- CD44
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背景
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The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined.
Alias Symbols: CDW44, CSPG8, ECMR-III, HCELL, IN, LHR, MC56, MDU2, MDU3, MGC10468, MIC4, MUTCH-I, Pgp1, HUTCH-I
Protein Interaction Partner: UBC, NF2, NEDD8, BAG1, DPP8, VHL, SRC, ANK1, ATF2, FMNL1, IQGAP1, SLC3A2, STAT3, ITGB1, FLOT2, EP300, CAV1, PRKCZ, ELAVL1, ARHGEF12, ARHGEF1, PKN1, DMP1, HMMR, TIAM1, ERBB4, VAV2, GARS, TGFBR2, TGFBR1, CD4, MMP7, SRGN, SPP1, LCK, IGFBP3, CD74, FYN, FGF2,
Protein Size: 361 -
分子量
- 40 kDa
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基因ID
- 960
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NCBI登录号
- NM_001001391, NP_001001391
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UniProt
- P16070
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途径
- Glycosaminoglycan Metabolic Process, Autophagy, Negative Regulation of intrinsic apoptotic Signaling
抗原
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