FLT1 抗体 (C-Term)
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北京 101111
Quick Overview for FLT1 抗体 (C-Term) (ABIN2788655)
抗原
See all FLT1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- DLRVTSKSKE SGLSDVSRPS FCHSSCGHVS EGKRRFTYDH AELERKIACC
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预测反应
- Cow: 93%, Dog: 100%, Goat: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Rabbit: 77%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against FLT1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human FLT1
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 1 mg/mL
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeat freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- FLT1 (Fms-Related tyrosine Kinase 1 (VEGFR1) (FLT1))
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别名
- FLT1
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背景
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This gene encodes a member of the vascular endothelial growth factor receptor (VEGFR) family. VEGFR family members are receptor tyrosine kinases (RTKs) which contain an extracellular ligand-binding region with seven immunoglobulin (Ig)-like domains, a transmembrane segment, and a tyrosine kinase (TK) domain within the cytoplasmic domain. This protein binds to VEGFR-A, VEGFR-B and placental growth factor and plays an important role in angiogenesis and vasculogenesis. Expression of this receptor is found in vascular endothelial cells, placental trophoblast cells and peripheral blood monocytes. Multiple transcript variants encoding different isoforms have been found for this gene. Isoforms include a full-length transmembrane receptor isoform and shortened, soluble isoforms. The soluble isoforms are associated with the onset of pre-eclampsia.
Protein Interaction Partner: SRPK1, VEGFA, Nedd4, UBC, ATR, NRP2, NRP1, VEGFB, PTK2B, PGF, PTK2, SHC1, NCK1, PLCG2, KDR, PTPN11, PLCG1, FLT1, YES1, CRK, FYN, CTNNB1, GRB2, SHC2, PIK3R1,
Protein Size: 463 -
分子量
- 50 kDa
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基因ID
- 2321
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途径
- RTK signaling, Signaling Events mediated by VEGFR1 and VEGFR2, VEGFR1 Specific Signals
抗原
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