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IL-18 抗体 (C-Term)

This anti-IL-18 antibody is a 兔 多克隆 antibody detecting IL-18 in WB. Suitable for 人, 小鼠 和 大鼠.
产品编号 ABIN2788556
发货至: 中国

Quick Overview for IL-18 抗体 (C-Term) (ABIN2788556)

抗原

See all IL-18 (IL18) 抗体
IL-18 (IL18) (Interleukin 18 (IL18))

适用

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人, 小鼠, 大鼠

宿主

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克隆类型

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多克隆

标记

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This IL-18 antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    C-Term

    序列

    IIFFQRSVPG HDNKMQFESS SYEGYFLACE KERDLFKLIL KKEDELGDRS

    预测反应

    Human: 100%, Mouse: 79%, Rat: 79%

    产品特性

    This is a rabbit polyclonal antibody against IL18. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human IL18
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 193 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    IL-18 (IL18) (Interleukin 18 (IL18))

    别名

    IL18

    背景

    The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.
    Alias Symbols: IGIF, IL-18, IL-1g, IL1F4, MGC12320
    Protein Interaction Partner: CASK, UBC, IL1RL2, IL18RAP, IL18R1, IL18BP, CASP4, CASP3, CASP1,
    Protein Size: 193

    分子量

    18 kDa

    基因ID

    3606

    NCBI登录号

    NM_001562, NP_001553

    UniProt

    Q14116

    途径

    Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
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