IL-18 抗体 (C-Term)
Quick Overview for IL-18 抗体 (C-Term) (ABIN2788556)
抗原
See all IL-18 (IL18) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- IIFFQRSVPG HDNKMQFESS SYEGYFLACE KERDLFKLIL KKEDELGDRS
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预测反应
- Human: 100%, Mouse: 79%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against IL18. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human IL18
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 193 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- IL-18 (IL18) (Interleukin 18 (IL18))
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别名
- IL18
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背景
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The protein encoded by this gene is a proinflammatory cytokine. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity.
Alias Symbols: IGIF, IL-18, IL-1g, IL1F4, MGC12320
Protein Interaction Partner: CASK, UBC, IL1RL2, IL18RAP, IL18R1, IL18BP, CASP4, CASP3, CASP1,
Protein Size: 193 -
分子量
- 18 kDa
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基因ID
- 3606
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NCBI登录号
- NM_001562, NP_001553
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UniProt
- Q14116
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途径
- Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome
抗原
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