GADD45A 抗体 (C-Term)
Quick Overview for GADD45A 抗体 (C-Term) (ABIN2788360)
抗原
See all GADD45A 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- LRVSNPGRLA ELLLLETDAG PAASEGAEQP PDLHCVLVTN PHSSQWKDPA
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预测反应
- Cow: 100%, Horse: 79%, Human: 100%, Pig: 93%, Rabbit: 86%
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产品特性
- This is a rabbit polyclonal antibody against GADD45A. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human GADD45A
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 165 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GADD45A (Growth Arrest and DNA-Damage-Inducible, alpha (GADD45A))
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别名
- GADD45A
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背景
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GADD45A responds to environmental stresses by mediating activation of the p38/JNK pathway via MTK1/MEKK4 kinase. The DNA damage-induced transcription of GADD45A gene is mediated by both p53-dependent and -independent mechanisms.
Alias Symbols: DDIT1, GADD45
Protein Interaction Partner: ING4, UBC, AURKA, STAT3, PCNA, MTOR, CDK1, APEX1, DCTN2, RPS7, MDM2, MAPK1, TIAL1, HNRNPA0, SH3GLB1, PTPRK, PSMC3, NUCB2, CDK11A, ASCC2, FAS, CCNB1, DNMT1, JMJD1C, UBR1, SYNE4, MIDN, IGSF21, FBN3, FAM83D, MICAL1, SPTBN4, NRBP1, DNAJC13, ZHX1, C14orf1, ADA
Protein Size: 165 -
分子量
- 18 kDa
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基因ID
- 1647
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NCBI登录号
- NM_001924, NP_001915
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UniProt
- P24522
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途径
- p53 Pathway, Cell Division Cycle
抗原
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