AP2A2 抗体 (C-Term)
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北京 101111
Quick Overview for AP2A2 抗体 (C-Term) (ABIN2788288)
抗原
See all AP2A2 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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原理
- AP2A2 Antibody - C-terminal region
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序列
- LAKLKKKKGP STVTDLEDTK RDRSVDVNGG PEPAPASTSA VSTPSPSADL
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预测反应
- Dog: 79%, Guinea Pig: 79%, Human: 100%, Mouse: 79%, Rat: 79%
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产品特性
- This is a rabbit polyclonal antibody against AP2A2. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human AP2A2
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anti-Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2) (AA 686-825) antibody
AP2A2 适用: 人, 小鼠, 大鼠 WB, IHC, ELISA, FACS, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2) (AA 590-939) antibodyAP2A2 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2) (AA 590-939) antibodyAP2A2 适用: 人 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2) (AA 610-637) antibodyAP2A2 适用: 人 WB, FACS, IHC (p) 宿主: 兔 Polyclonal RB22030 unconjugated
anti-Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2) (Internal Region) antibodyAP2A2 适用: 人, 小鼠, 大鼠 WB, IHC, IF, ICC 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2) (AA 21-150) antibodyAP2A2 适用: 人 WB, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2) antibodyAP2A2 适用: 人 WB, IHC, FACS 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2) (AA 612-661) antibodyAP2A2 适用: 人, 小鼠, 大鼠, 犬, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2) (C-Term) antibodyAP2A2 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP59974-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- AP2A2 (Adaptor-Related Protein Complex 2, alpha 2 Subunit (AP2A2))
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别名
- AP2A2
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背景
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Targeted Subunit: alpha-2
Background Information: AP2A2 is a component of the adaptor protein complex 2 (AP-2). AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. AP-2 also serves as a cargo receptor to selectively sort the membrane proteins involved in receptor-mediated endocytosis. AP-2 seems to play a role in the recycling of synaptic vesicle membranes from the presynaptic surface. AP-2 recognizes Y-X-X-[FILMV] (Y-X-X-Phi) and [ED]-X-X-X-L-[LI] endocytosis signal motifs within the cytosolic tails of transmembrane cargo molecules. AP-2 may also play a role in maintaining normal post-endocytic trafficking through the ARF6-regulated, non-clathrin pathway. The AP-2 alpha subunit binds polyphosphoinositide-containing lipids, positioning AP-2 on the membrane. The AP-2 alpha subunit acts via its C-terminal appendage domain as a scaffolding platform for endocytic accessory proteins. The AP-2 alpha and AP-2 sigma subunits are thought to contribute to the recognition of the [ED]-X-X-X-L-[LI] motif .
Gene Name: Adaptor-related protein complex 2, alpha 2 subunit
Alternative Symbols: HIP9, HYPJ, ADTAB, HIP-9, CLAPA2
Protein Name: AP-2 complex subunit alpha-2
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分子量
- 104kDa
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基因ID
- 161
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NCBI登录号
- NP_036437
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UniProt
- O94973
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途径
- EGFR Signaling Pathway, Neurotrophin Signaling Pathway, EGFR Downregulation, SARS-CoV-2 Protein Interactome
抗原
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