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- 抗原 See all GCH1 抗体
- GCH1 (GTP Cyclohydrolase 1 (GCH1))
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抗原表位
- N-Term
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适用
- 人, 大鼠, Cow, 犬, 兔
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This GCH1 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 序列
- PPRPEAKSAQ PADGWKGERP RSEEDNELNL PNLAAAYSSI LSSLGENPQR
- 预测反应
- Cow: 100%, Dog: 100%, Human: 100%, Rabbit: 100%, Rat: 86%
- 产品特性
- This is a rabbit polyclonal antibody against GCH1. It was validated on Western Blot.
- 纯化方法
- Affinity Purified
- 免疫原
- The immunogen is a synthetic peptide directed towards the N-terminal region of Human GCH1
- Top Product
- Discover our top product GCH1 Primary Antibody
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anti-GTP Cyclohydrolase 1 (GCH1) (AA 84-172) antibody
GCH1 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 4A12 unconjugated
anti-GTP Cyclohydrolase 1 (GCH1) (AA 1-250) antibodyGCH1 适用: 人 WB, IF 宿主: 兔 Polyclonal unconjugated
anti-GTP Cyclohydrolase 1 (GCH1) (Internal Region) antibodyVerified GCH1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-GTP Cyclohydrolase 1 (GCH1) antibodyGCH1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GTP Cyclohydrolase 1 (GCH1) (AA 1-250) antibodyGCH1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 2C4 unconjugated
anti-GTP Cyclohydrolase 1 (GCH1) (AA 1-250) antibodyGCH1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1F5 unconjugated
anti-GTP Cyclohydrolase 1 (GCH1) (AA 1-250) antibodyGCH1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-GTP Cyclohydrolase 1 (GCH1) (AA 34-110) antibodyGCH1 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-GTP Cyclohydrolase 1 (GCH1) (AA 1-250) antibodyGCH1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-GTP Cyclohydrolase 1 (GCH1) (AA 84-172) antibodyGCH1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 注意事项
- Avoid repeat freeze-thaw cycles.
- 储存条件
- -20 °C
- 储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- 抗原
- GCH1 (GTP Cyclohydrolase 1 (GCH1))
- 别名
- GCH1 (GCH1 产品)
- 别名
- DYT14 antibody, DYT5 antibody, DYT5a antibody, GCH antibody, GTP-CH-1 antibody, GTPCH1 antibody, HPABH4B antibody, GTP-CH antibody, GTPCH antibody, Gch antibody, MGC89622 antibody, gch1a antibody, wu:fc16b10 antibody, zgc:195269 antibody, GTP cyclohydrolase 1 antibody, GTP cyclohydrolase 1-like antibody, GCH1 antibody, Gch1 antibody, gch1 antibody, Weevi_1190 antibody, Halhy_0838 antibody, Sinme_1220 antibody, Sphch_1077 antibody, LOC100136794 antibody
- 背景
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This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described, however, not all variants give rise to a functional enzyme.
Protein Interaction Partner: GCH1, CALML6, CAMKK1, CSNK1G1, CALML5, PACSIN3, RGS19, MAP2K4, MAPK12, MAP2K5, MAPK10, PRKAR2B, PRKAR2A, PPM1B, CSNK2B, CSNK2A1, GIT2, YWHAZ, CNRIP1, RAB26, AHSA1, SP3, RLF, HSPA8, GCHFR, ATP1B1, CDC37, SH3GL2, OSBPL9, RPH3A,
Protein Size: 250 - 分子量
- 27 kDa
- 基因ID
- 2643
- UniProt
- P30793
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