GCH1 抗体 (C-Term)
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Quick Overview for GCH1 抗体 (C-Term) (ABIN2788138)
抗原
See all GCH1 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- C-Term
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序列
- LRPAGVGVVV EATHMCMVMR GVQKMNSKTV TSTMLGVFRE DPKTREEFLT
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预测反应
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Yeast: 85%, Zebrafish: 93%
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产品特性
- This is a rabbit polyclonal antibody against GCH1. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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免疫原
- The immunogen is a synthetic peptide directed towards the C terminal region of human GCH1
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anti-GTP Cyclohydrolase 1 (GCH1) (AA 84-172) antibody
GCH1 适用: 人 WB, ELISA, IHC (p), IP 宿主: 小鼠 Monoclonal 4A12 unconjugated
anti-GTP Cyclohydrolase 1 (GCH1) (Internal Region) antibodyVerified GCH1 适用: 人 ELISA, IHC 宿主: 山羊 Polyclonal unconjugated
anti-GTP Cyclohydrolase 1 (GCH1) antibodyGCH1 适用: 人 WB, ELISA, IHC 宿主: 兔 Polyclonal unconjugated
anti-GTP Cyclohydrolase 1 (GCH1) antibodyKD Validated GCH1 适用: 人 WB 宿主: 小鼠 Monoclonal 24GB13125 unconjugated
anti-GTP Cyclohydrolase 1 (GCH1) (AA 1-250) antibodyGCH1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 2C4 unconjugated
anti-GTP Cyclohydrolase 1 (GCH1) (AA 1-250) antibodyGCH1 适用: 人 ELISA, IF 宿主: 小鼠 Monoclonal 1F5 unconjugated
anti-GTP Cyclohydrolase 1 (GCH1) (AA 1-250) antibodyGCH1 适用: 人 WB, IF 宿主: 小鼠 Polyclonal unconjugated
anti-GTP Cyclohydrolase 1 (GCH1) (AA 34-110) antibodyGCH1 适用: 小鼠 WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro) 宿主: 兔 Polyclonal unconjugated
anti-GTP Cyclohydrolase 1 (GCH1) (AA 84-172) antibodyGCH1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
anti-GTP Cyclohydrolase 1 (GCH1) (AA 1-250) antibodyGCH1 适用: 人 WB, ELISA 宿主: 小鼠 Polyclonal unconjugated
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 250 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- GCH1 (GTP Cyclohydrolase 1 (GCH1))
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别名
- GCH1
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背景
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This gene encodes a member of the GTP cyclohydrolase family. The encoded protein is the first and rate-limiting enzyme in tetrahydrobiopterin (BH4) biosynthesis, catalyzing the conversion of GTP into 7,8-dihydroneopterin triphosphate. BH4 is an essential cofactor required by aromatic amino acid hydroxylases as well as nitric oxide synthases. Mutations in this gene are associated with malignant hyperphenylalaninemia and dopa-responsive dystonia. Several alternatively spliced transcript variants encoding different isoforms have been described, however, not all variants give rise to a functional enzyme.
Alias Symbols: DYT14, DYT5, DYT5a, GCH, GTP-CH-1, GTPCH1, HPABH4B
Protein Interaction Partner: GCH1, CALML6, CAMKK1, CSNK1G1, CALML5, PACSIN3, RGS19, MAP2K4, MAPK12, MAP2K5, MAPK10, PRKAR2B, PRKAR2A, PPM1B, CSNK2B, CSNK2A1, GIT2, YWHAZ, CNRIP1, RAB26, AHSA1, SP3, RLF, HSPA8, GCHFR, ATP1B1, CDC37, SH3GL2, OSBPL9, RPH3A,
Protein Size: 250 -
分子量
- 28 kDa
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基因ID
- 2643
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NCBI登录号
- NM_000161, NP_000152
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UniProt
- P30793
抗原
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