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PC (C-Term) 抗体

This anti- antibody is a 兔 多克隆 antibody detecting in WB. Suitable for 人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马 和 Pig.
产品编号 ABIN2788135
发货至: 中国

Quick Overview for PC (C-Term) 抗体 (ABIN2788135)

抗原

PC

适用

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人, 小鼠, 大鼠, Cow, 犬, 豚鼠, 马, Pig

宿主

  • 14

克隆类型

  • 13
  • 1
多克隆

标记

  • 11
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非结合性

应用范围

  • 11
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Western Blotting (WB)
  • 抗原表位

    • 4
    • 3
    • 2
    • 1
    • 1
    • 1
    C-Term

    序列

    SLPPLDLQAL EKELVDRHGE EVTPEDVLSA AMYPDVFAHF KDFTATFGPL

    预测反应

    Cow: 86%, Dog: 86%, Guinea Pig: 79%, Horse: 86%, Human: 100%, Mouse: 86%, Pig: 86%, Rat: 86%

    产品特性

    This is a rabbit polyclonal antibody against PC. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the C terminal region of human PC
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 1178 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    PC

    背景

    This gene encodes pyruvate carboxylase, which requires biotin and ATP to catalyse the carboxylation of pyruvate to oxaloacetate. The active enzyme is a homotetramer arranged in a tetrahedron which is located exclusively in the mitochondrial matrix. Pyruvate carboxylase is involved in gluconeogenesis, lipogenesis, insulin secretion and synthesis of the neurotransmitter glutamate. Mutations in this gene have been associated with pyruvate carboxylase deficiency. Alternatively spliced transcript variants with different 5' UTRs, but encoding the same protein, have been found for this gene.
    Alias Symbols: PCB
    Protein Interaction Partner: HUWE1, SUMO2, UBC, SUMO1, MDM2, HECW2, ADRB2, IFIT1, PRKCDBP, PPT2, TUFM, RPS3A, NACA, MTHFD1, ILF3, ILF2, CDH2, UBE2N, NPM1, MDH2, GOT2, GOT1,
    Protein Size: 1178

    分子量

    127 kDa

    基因ID

    5091

    NCBI登录号

    NM_001040716, NP_001035806

    UniProt

    P11498
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