alpha 2 Macroglobulin 抗体 (N-Term)
Quick Overview for alpha 2 Macroglobulin 抗体 (N-Term) (ABIN2787981)
抗原
See all alpha 2 Macroglobulin (A2M) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- N-Term
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序列
- PVPGHVTVSI CRKYSDASDC HGEDSQAFCE KFSGQLNSHG CFYQQVKTKV
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预测反应
- Human: 100%
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产品特性
- This is a rabbit polyclonal antibody against A2M. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilutions should be determined experimentally by the investigator.
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说明
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Antigen size: 1474 AA
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- Lot specific
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缓冲液
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- Avoid repeated freeze-thaw cycles.
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储存条件
- -20 °C
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储存方法
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- alpha 2 Macroglobulin (A2M) (alpha-2-Macroglobulin (A2M))
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别名
- A2M
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背景
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Alpha-2-macroglobulin is a protease inhibitor and cytokine transporter. It inhibits many proteases, including trypsin, thrombin and collagenase. A2M is implicated in Alzheimer disease (AD) due to its ability to mediate the clearance and degradation of A-beta, the major component of beta-amyloid deposits.
Alias Symbols: CPAMD5, DKFZp779B086, FWP007, S863-7, A2MD
Protein Interaction Partner: MAPK6, CDK7, CDK11A, HIPK1, FBXO6, CFTR, TP63, TGM2, IFIT3, DNAJB1, GCDH, FARSA, ENO2, ELAVL3, CYP2C18, CYP2C8, ATP1A1, APP, APOE, ACTB, A2M, RNF32, SWSAP1, TRAPPC5, EVI5L, EGLN2, IGSF8, PRAM1, MLST8, STAMBPL1, RETN, FBXL12, ECSIT, FIS1, EXOSC1, IFIT5, NC
Protein Size: 1474 -
分子量
- 161 kDa
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基因ID
- 2
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NCBI登录号
- NM_000014, NP_000005
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UniProt
- P01023
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途径
- Lipid Metabolism
抗原
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