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CD3 epsilon 抗体 (Middle Region)

This 兔 多克隆 antibody specifically detects CD3 epsilon in WB. It exhibits reactivity toward 人.
产品编号 ABIN567466
发货至: 中国
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Quick Overview for CD3 epsilon 抗体 (Middle Region) (ABIN567466)

抗原

See all CD3 epsilon (CD3E) 抗体
CD3 epsilon (CD3E)

适用

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宿主

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克隆类型

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多克隆

标记

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This CD3 epsilon antibody is un-conjugated

应用范围

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Western Blotting (WB)
  • 抗原表位

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    Middle Region

    序列

    QYPGSEILWQ HNDKNIGGDE DDKNIGSDED HLSLKEFSEL EQSGYYVCYP

    预测反应

    Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against CD3E. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human CD3E
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 207 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    CD3 epsilon (CD3E)

    别名

    CD3E

    背景

    The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.
    Alias Symbols: FLJ18683, T3E, TCRE
    Protein Interaction Partner: UBC, CSK, ZAP70, SNTA1, PTPN22, PIK3R2, PIK3R1, LAT, LCK, CD38, CD247, CD3G, TRAT1, NCK2, UNC119, SHC1, NCK1, SYK, CD3D, NCL, CD79B, TOP2B, CD3EAP, JAK3,
    Protein Size: 207

    分子量

    23 kDa

    基因ID

    916

    NCBI登录号

    NM_000733, NP_000724

    UniProt

    P07766

    途径

    TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway
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