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Caspase 10 抗体 (Middle Region)

The 兔 多克隆 anti-Caspase 10 antibody (ABIN567450) specifically detects Caspase 10 in WB. The antibody is reactive with 人 samples.
产品编号 ABIN567450
发货至: 中国
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北京 101111
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Quick Overview for Caspase 10 抗体 (Middle Region) (ABIN567450)

抗原

See all Caspase 10 (CASP10) 抗体
Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

适用

  • 99
  • 24
  • 5

宿主

  • 91
  • 5
  • 2
  • 1

克隆类型

  • 65
  • 34
多克隆

标记

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This Caspase 10 antibody is un-conjugated

应用范围

  • 60
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  • 17
  • 13
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  • 8
  • 3
  • 1
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Western Blotting (WB)
  • 抗原表位

    • 16
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    • 1
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    Middle Region

    序列

    HNNVTKVEME MVLQKQKCNP AHADGDCFVF CILTHGRFGA VYSSDEALIP

    预测反应

    Human: 100%

    产品特性

    This is a rabbit polyclonal antibody against CASP10. It was validated on Western Blot.

    纯化方法

    Affinity Purified

    免疫原

    The immunogen is a synthetic peptide directed towards the middle region of human CASP10
  • 应用备注

    Optimal working dilutions should be determined experimentally by the investigator.

    说明

    Antigen size: 479 AA

    限制

    仅限研究用
  • 状态

    Liquid

    浓度

    Lot specific

    缓冲液

    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

    储存液

    Sodium azide

    注意事项

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    注意事项

    Avoid repeated freeze-thaw cycles.

    储存条件

    -20 °C

    储存方法

    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • 抗原

    Caspase 10 (CASP10) (Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))

    别名

    CASP10

    背景

    This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome. Three alternatively spliced transcript variants encoding different isoforms have been described for this gene.
    Alias Symbols: ALPS2, FLICE2, MCH4
    Protein Interaction Partner: FADD, PRDX6, XIAP, RB1, Dlg4, PHF20L1, OIP5, ECE2, RIOK3, NFKBIL1, CASP8, RNF34, BFAR, CASP8AP2, MSN2, PTC2, AIM9, GLN3, SLT2, GPA1, STE20, ATG13, RPL21B, VPS30, CUP9, TPK2, GAL4, FAR11, WHI3, ATG4, FAR3, FAR8, ITT1, MPH1, SSM4, ASG1, BFR1, ORT1, MBR1, CW
    Protein Size: 479

    分子量

    12 kDa

    基因ID

    843

    NCBI登录号

    NM_001230, NP_001221

    UniProt

    Q92851

    途径

    Apoptosis, Caspase Cascade in Apoptosis
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