BNIP3L/NIX 抗体 (Middle Region)
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北京 101111
Quick Overview for BNIP3L/NIX 抗体 (Middle Region) (ABIN2787863)
抗原
See all BNIP3L/NIX (BNIP3L) 抗体适用
宿主
克隆类型
标记
应用范围
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抗原表位
- Middle Region
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原理
- Bnip3l Antibody - middle region
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序列
- CDSPSPQEDG QIMFDVEMHT SRDHSSQSEE EVVEGEKEVE ALKKSADWVS
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预测反应
- Cow: 93%, Dog: 100%, Guinea Pig: 92%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
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产品特性
- This is a rabbit polyclonal antibody against Bnip3l. It was validated on Western Blot.
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纯化方法
- Affinity Purified
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应用备注
- Optimal working dilution should be determined by the investigator.
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说明
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We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP58878-100UG
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限制
- 仅限研究用
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状态
- Liquid
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浓度
- 0.5 mg/mL
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缓冲液
- Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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储存液
- Sodium azide
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注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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注意事项
- prevent freeze-thaw cycles
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储存条件
- 4 °C,-20 °C
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储存方法
- For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.
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- BNIP3L/NIX (BNIP3L) (BCL2/adenovirus E1B 19kDa Interacting Protein 3-Like (BNIP3L))
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别名
- Bnip3l
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背景
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Background Information: Bnip3l induces apoptosis. It interacts with viral and cellular anti-apoptosis proteins. It can overcome the suppressors BCL-2 and BCL-XL, although high levels of BCL-XL expression will inhibit apoptosis. It inhibits apoptosis induced by BNIP3. It is involved in mitochondrial quality control via its interaction with SPATA18/MIEAP: in response to mitochondrial damage, participates to mitochondrial protein catabolic process (also named MALM) leading to the degradation of damaged proteins inside mitochondria. Bnip3l may function as a tumor suppressor.
Gene Name: BCL2/adenovirus E1B interacting protein 3-like
Alternative Symbols: N, Nix, Nip3L, C86132, D14Ertd719, D14Ertd719e
Protein Name: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
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分子量
- 24kDa
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基因ID
- 12177
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NCBI登录号
- NP_033891
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UniProt
- Q9Z2F7
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途径
- Autophagy
抗原
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